DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doc2 and tbx-34

DIOPT Version :9

Sequence 1:	NP_648282.1	Gene:	Doc2 / 39038	FlyBaseID:	FBgn0035956	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_499441.1	Gene:	tbx-34 / 176549	WormBaseID:	WBGene00006553	Length:	302	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	54/228 - (23%)
Similarity:	95/228 - (41%)	Gaps:	36/228 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKFSG 120
            :::::.|:..:::...: .||::.:.|.:|.|..:..:|||.|...|.:.|.:....:.||.:..
Worm     1 MQVSIVNEHKYRELEPL-NEMLVKRGGVKMIPEPKFVISGLVDNEEYVIKLRIDLADEFRYSYQN 64

  Fly   121 SQWVPAGGAEPQSPQRMYLHPD-SPATGAHWQAQPILFNKVKLTNNTLDNSGHIV-LASMHKYQP 183
            .||.|...:...|........: ...|||.|..:.:.|:|:.:|....|...::: :...|||.|
Worm    65 QQWTPFAPSTKNSKLSAITETEHRKETGATWNMRIVQFDKLLITREFNDIQRNVIHVEPNHKYIP 129

  Fly   184 RLHVIRTADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKM 248
            .|      .:..:.......|.|.:.||:||.:||:.||...|                |..|||
Worm   130 VL------TIQNVTTGKSTEFQFQQMEFIAVKSYQSARIRHTK----------------RAPRKM 172

  Fly   249 SSSPTGEDQDQ--SPSLSHSQSQSESDMSPTKG 279
            :.:|....:.|  .|.:.|         |||.|
Worm   173 NLAPGSSQKPQLIVPDILH---------SPTYG 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	42/187 (22%)
tbx-34	NP_499441.1	T-box	3..166	CDD:279278	41/169 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910