Protein Alignment Doc2 and tbx-2

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001370674.1
• Gene: tbx-2 / 175698
• WormBaseID: WBGene00006543
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 453
• Identity: 165/453 - (36%)
• Similarity: 235/453 - (51%)
• Gaps: 84/453 - (18%)

  Fly    34 PPMLPIPM------PRHVIMPPR---VT-LPGVEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPS 88
            ||.|...|      |..|..||.   || .|.||  |...:||:||.|.||||:|||||||:||:
 Worm    31 PPNLFFSMLQAGFPPGPVGSPPEDDGVTDDPKVE--LDERELWQQFSQCGTEMVITKSGRRIFPA 93

  Fly    89 MRLSVSGLEDESNYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQ 153
            .|:.:|||:.:|.|.|::::||..:.||||:.|:|:.||.|:|:.|:.:|:|||||:||.||.::
 Worm    94 YRVKISGLDKKSQYFVMMDLVPADEHRYKFNNSRWMIAGKADPEMPKTLYIHPDSPSTGEHWMSK 158

  Fly   154 PILFNKVKLTNNTLDNSGHIVLASMHKYQPRLHVIRTADLAQIPWAPQQAFVFAETEFVAVTAYQ 218
            ...|:|:|||||..|..|:.:|.|||||||||||:|.||...:.::..:.|||.||||:||||||
 Worm   159 GANFHKLKLTNNISDKHGYTILNSMHKYQPRLHVVRCADRHNLMYSTFRTFVFRETEFIAVTAYQ 223

  Fly   219 NDRITKLKIDNNPFAKGFRETGQSRCKRKMSSSPTGEDQDQSP-----SL-SHSQSQSESDMSPT 277
            |:::|:|||:|||||||||:.|..:.::|........|..|||     || :||...|||:
 Worm   224 NEKVTELKIENNPFAKGFRDAGAGKREKKRQLHRMNGDATQSPPGKTASLPTHSPHPSESN---- 284

  Fly   278 KGGGETAGGTSSIGDSDGPQIKRLRSNGSACSLSSSLDDQSVPGASSLALGSPPPHLHSHSHPHP 342
                         .:.|.|.:|:.:...|....:|||..            |..|.|.:|   ||
 Worm   285 -------------SEDDEPTLKKCKPEPSQTPTTSSLST------------STTPTLSAH---HP 321

  Fly   343 LQARSASSVFMQHFQQNMQSLLRPSLVDLACTYFGRPHEYGGAIQASPMYPPAAMLQAGLGPHPG 407
            |::               .....|..:|:  .|...|.:.....|.:.::|..:|         .
 Worm   322 LRS---------------PQFCIPPPIDM--MYQNMPMDLLAHWQMATLFPQFSM---------A 360

  Fly   408 LNLPPGVSGADLISDE--SGAEELELDVGSETSTLEQSTQEQPLEQPST---RSKGFSISAIL 465
            ||.|  .:.|.|:|..  ..:.|.:::..||.|. |....|...||.|.   :..||.:..:|
 Worm   361 LNSP--AAAASLLSKHLAKASSECKVEATSEDSE-EAEKPEVKKEQKSVTPPKKGGFDVLDLL 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	103/186 (55%)
tbx-2	NP_001370674.1	T-box_TBX2_3-like	59..243	CDD:410314	102/185 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	243	1.000	Inparanoid score	I2074
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.860