Protein Alignment Doc2 and Eomes

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_034266.2
• Gene: Eomes / 13813
• MGIID: 1201683
• Length: 707
• Species: Mus musculus
• Alignment Length: 455
• Identity: 145/455 - (31%)
• Similarity: 209/455 - (45%)
• Gaps: 87/455 - (19%)

  Fly    53 LPG----VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGD 113
            :||    ..:.|.|..||.:||:..|||||||.||||||.:..:::||...::|.|.:|:|....
Mouse   262 VPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADP 326

  Fly   114 CRYKFSGSQWVPAGGAE-PQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNN---TLDNSGHIV 174
            ..::|.|.:||..|.|: .....:||:||:||.||:||..|.|.|.|:|||||   ..:|:..||
Mouse   327 NHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIV 391

  Fly   175 LASMHKYQPRLHVIRTA-----DLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAK 234
            |.|:||||||||::...     ||.: | :..|.|.|:||:|:|||||||..||:||||:|||||
Mouse   392 LQSLHKYQPRLHIVEVTEDGVEDLNE-P-SKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAK 454

  Fly   235 GFRETGQSRC----KRKMSSSPTGEDQDQSPSLSHSQSQSESDMSP-----TKGGGETAGGTSSI 290
            |||:...|..    ..:::.|||  |..:|..:.........:..|     |........|..::
Mouse   455 GFRDNYDSMYTASENDRLTPSPT--DSPRSHQIVPGGRYGVQNFFPEPFVNTLPQARYYNGERTV 517

  Fly   291 GDSDG---PQIKRLRSNGSACSLSSSLDDQSVPGASSLALGSPPPHLHSHSHPHPLQARSASSVF 352
            ..::|   ||.....:|.....|.:.:..   |..:.|.:||             .::...||..
Mouse   518 PQTNGLLSPQQSEEVANPPQRWLVTPVQQ---PVTNKLDIGS-------------YESEYTSSTL 566

  Fly   353 MQHFQQNMQSLLRPSLVDLACTYFGRPHEYGGAIQASPMYPPAA----------MLQAGLGPHPG 407
            :.:   .::||  |.....|..|:           ..|.:|..|          .:.||| |...
Mouse   567 LPY---GIKSL--PLQTSHALGYY-----------PDPTFPAMAGWGGRGAYQRKMAAGL-PWTS 614

  Fly   408 LNLPPGVSGADLISDESGAEEL------------ELDVGSETSTLEQSTQEQPLEQPSTRSKGFS 460
            ...|| |...|.::.|...||:            .||  |..|.:..|..::....|||.|.|.|
Mouse   615 RMSPP-VFPEDQLAKEKVKEEISSSWIETPPSIKSLD--SSDSGVYNSACKRKRLSPSTPSNGNS 676

  Fly   461  460
            Mouse   677  676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	94/199 (47%)
Eomes	NP_034266.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..125
		TBOX	269..462	CDD:238106	93/194 (48%)
		T-box_assoc	484..705	CDD:292794	44/229 (19%)
		Required for transcription activation. /evidence=ECO:0000250	592..707		23/89 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	642..689		11/37 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910