Protein Alignment Doc3 and tbx21

DIOPT Version :10

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001164070.1
• Gene: tbx21 / 797797
• ZFINID: ZDB-GENE-080104-3
• Length: 609
• Species: Danio rerio
• Alignment Length: 481
• Identity: 151/481 - (31%)
• Similarity: 213/481 - (44%)
• Gaps: 118/481 - (24%)

  Fly    30 PDPLCGLLPNFAGHFMPPPPPPQPTLPG-DVEAK----LENNELWQQFHSIGTEMIITKCGRRMF 89
            |....|...:|...|   |..|..:||| .|..|    |.|..||.:||...|||||||.|||||
Zfish   120 PSSADGYTASFQHGF---PRAPMYSLPGLQVSGKTQVLLNNYPLWAKFHKYQTEMIITKQGRRMF 181

  Fly    90 PSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSP-QRMYLHPESPATGKHW 153
            |.:..:::.|:..|.|.:.:::|......:::.|.:||..|.||...| .|||:||:||.||.||
Zfish   182 PFLSFNITSLDPSAHYNIYVDVVLADQHHWRYQGGKWVQCGKAEGNMPGNRMYMHPDSPNTGTHW 246

  Fly   154 QSQALLFSKVKLTNNTLDNNG---HIVLASMHKYQPRLHVIRTSDLG-QIPW--APQQAFIFPET 212
            ..|.:.|.|:|||||...:|.   .|||.|:||||||||::...:.| :.|:  :..|.|:||||
Zfish   247 MRQEVSFGKLKLTNNKGSSNNVAQMIVLQSLHKYQPRLHIVEVKEDGTEDPFLTSKTQTFVFPET 311

  Fly   213 EFIAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKIND--SPPPTQ---------------- 259
            :|||||||||..||:||||:||||||||::..:.......|  :|.||:
Zfish   312 QFIAVTAYQNADITQLKIDHNPFAKGFRDNYDTLYAPPDPDRLTPSPTESQQLLSGSCYPHQPYL 376

  Fly   260 --------PEANQVDRSPV--TSPLAK---------------------RL------------RLV 281
                    |::....|.||  |.|..|                     ||            .|.
Zfish   377 SDQYMSPLPQSRFYSREPVSMTQPCPKDPTSSPHSRWYLSSQQAVPPNRLDFSAYETEYTSNSLY 441

  Fly   282 EEFP---QHHHHQSHHSV-PMQRHYLLDALEANFYVPAPPPPAIEYARHIGGAYP----SWAYTP 338
            :.||   ..||..|::|. |.....:..|....:.....|.|  :|..|...:.|    ||....
Zfish   442 KPFPLQSSPHHPLSYYSENPFTSGAVSSANPGAWTASGRPSP--QYLNHPHHSKPTSSLSWFRAV 504

  Fly   339 PSPASSVSSSSAGSTSGESAA-----------DREADADADTFVDVVGTAPAAPPPP-------- 384
            ||||:|.|.::..|....|.:           |:..::..||:::    ||:.....
Zfish   505 PSPAASSSPTATNSRFHASPSLLEPQRQPLLQDKSKESTEDTWIE----APSVKSVDSADSGLFE 565

  Fly   385 ---------SPPVPATATAPASSSSD 401
                     ||...:|..:|.:.|::
Zfish   566 GGESKKRRVSPYTSSTENSPPNRSAE 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	T-box_Drosocross-like	59..241	CDD:410332	94/192 (49%)
tbx21	NP_001164070.1	T-box_TBX21	150..340	CDD:410329	93/189 (49%)
		T-box_assoc	363..608	CDD:465042	43/235 (18%)