Protein Alignment Doc3 and eomesa

DIOPT Version :9

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_571754.3
• Gene: eomesa / 64603
• ZFINID: ZDB-GENE-001228-1
• Length: 661
• Species: Danio rerio
• Alignment Length: 480
• Identity: 152/480 - (31%)
• Similarity: 208/480 - (43%)
• Gaps: 122/480 - (25%)

  Fly    33 LCGLLPNFAGHFM---------PPPPPPQPTL-----PGD-----VEAKLENNELWQQFHSIGTE 78
            :|.....|.|.:.         |..|.|..:|     ||.     .:..|.|..||.:||...||
Zfish   165 VCASRSQFGGGYQFGQGPGCLYPSYPGPGSSLSSMPIPGSGSAARAQVYLCNRPLWLKFHRHQTE 229

  Fly    79 MIITKCGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAE-PQSPQRMYL 142
            |||||.||||||.:..:::||...|.|.|.:|:|......::|.|.:||..|.|: .....::|:
Zfish   230 MIITKQGRRMFPFLSFNITGLNLTAHYNVFVEIVLADPNHWRFQGGKWVTCGKADNNMQGNKVYV 294

  Fly   143 HPESPATGKHWQSQALLFSKVKLTNNTLDNNGH---IVLASMHKYQPRLHVIRTSDLG---QIPW 201
            |||||.||.||..|.:.|.|:|||||...||.:   |||.|:||||||||::..::.|   ....
Zfish   295 HPESPNTGAHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDMSSE 359

  Fly   202 APQQAFIFPETEFIAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKINDSPPPTQPEANQVD 266
            |..|.|.|||.:|||||||||..||:||||:||||||||::..|..          |.||::::.
Zfish   360 AKTQTFTFPENQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMY----------TAPESDRLT 414

  Fly   267 RSPVTSPLAKRL--------------RLVEEFPQHHH-HQSHHSVPM------------------ 298
            .||..||.:.::              :.|...||:|. :.|..:||.
Zfish   415 PSPTDSPRSHQIVPGARYAMQPFFQDQFVNNLPQNHRFYGSERAVPQTNGLLSPQSEDSAAGSAS 479

  Fly   299 -QRHYL-----------LD-----ALEANFYVPAPPPPAIEYARHIGGAYPSWAYTPPSPASSVS 346
             ||.::           ||     ...|:..:|....|....:.|..|.||..|:
Zfish   480 AQRWFVGPVQQSGATTKLDLSYDSEYSASSLLPYGIKPLPLQSPHALGYYPDSAF---------- 534

  Fly   347 SSSAGSTSGESAADREADADADTFVDVVGTAPAAPPPPSPPV--------------PATATAPAS 397
            :|.|...|..|:..|:           :.|.....|.||||.              ..:..||.:
Zfish   535 ASMAAGWSSRSSYQRK-----------MTTGLPWSPRPSPPAYTDDLLSSKDKLQDENSTAAPTA 588

  Fly   398 SSSDPTM-AKPKRSSFSISDILGTS 421
            :|:.|.| |.|...|....|..|.|
Zfish   589 ASTGPWMEAPPVLKSVDSGDTSGYS 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	94/198 (47%)
eomesa	NP_571754.3	TBOX	210..403	CDD:238106	94/192 (49%)
		T-box_assoc	425..659	CDD:292794	41/210 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910