DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doc3 and mgaa

DIOPT Version :9

Sequence 1:	NP_648280.1	Gene:	Doc3 / 39036	FlyBaseID:	FBgn0035954	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_005158676.1	Gene:	mgaa / 569620	ZFINID:	ZDB-GENE-030603-1	Length:	2838	Species:	Danio rerio

Alignment Length:	224	Identity:	102/224 - (45%)
Similarity:	135/224 - (60%)	Gaps:	17/224 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 PQPTLPGDVEAK-----LENNELWQQFHSIGTEMIITKCGRRMFPSMRVSLSGLEEEASYCVLLE 110
            |...||.|...:     |:||.:|.:||...||||:||.||||||..|..|||:|...:|.:.::
Zfish    87 PSENLPADARCRGITVTLDNNNMWNEFHRCKTEMILTKQGRRMFPYCRFRLSGMEPFQNYVLAMD 151

  Fly   111 MVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPESPATGKHWQSQALLFSKVKLTNNTLDNNGH 175
            :.|..:||||:||..|.|.|.|||.. .|:::||||||:|.||....:.|.::||. ||||..||
Zfish   152 IKPADNCRYKWSGKGWEPNGKAEPHI-SRLFVHPESPASGLHWMQYPVSFYRLKLC-NTLDQEGH 214

  Fly   176 IVLASMHKYQPRLHVIRTSDLGQ---IPWAPQQAFI-FPETEFIAVTAYQNDRITKLKIDNNPFA 236
            |:|.|||:|.|::|:|....:.:   |...|....: |.:|||.|||||||..||:||||.||||
Zfish   215 IILHSMHRYLPQIHIIPADKVSKDILILDRPNVVTLSFAQTEFFAVTAYQNLCITQLKIDYNPFA 279

  Fly   237 KGFRESG----QSRCKRKINDSPPPTQPE 261
            |||||..    .|:.|..:  |...|:.|
Zfish   280 KGFREDAVNARSSKAKNGL--STDETESE 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	94/199 (47%)
mgaa	XP_005158676.1	T-box	102..284	CDD:279278	91/183 (50%)
		DUF4801	1321..1366	CDD:292677
		NTR2	<2131..2271	CDD:292097
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910