Protein Alignment Doc3 and tbx-43

DIOPT Version :10

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001040883.1
• Gene: tbx-43 / 4363053
• WormBaseID: WBGene00044798
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 293
• Identity: 88/293 - (30%)
• Similarity: 133/293 - (45%)
• Gaps: 44/293 - (15%)

  Fly    63 LENNELWQQFHSIGTEMIITKCGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWV 127
            |....||::|.|...||||||.||.:||.:..:..||.|..:|.:.:.|.||...:.||:..:|.
 Worm     7 LMEKSLWREFDSQCNEMIITKIGRNLFPILEFAFKGLCEHLNYKIGVTMEPISYQKLKFTAGRWE 71

  Fly   128 PAGGAEPQ-SPQRMYLHPESPATGKHWQSQALLFSKVKLTN--NTLDNNGHIV-LASMHKYQPRL 188
            .....|.. .|..::|    ..:|:....:.|...|:||||  :.|..:..:: :.||.:|.|.|
 Worm    72 SLDIQEEMVQPNEVFL----MKSGRELLQRGLKLEKLKLTNSKDALQKSDQMIRVQSMRQYMPVL 132

  Fly   189 HVIRTSDLGQIPWAPQQ--AFIFPETEFIAVTAYQNDRITKLKIDNNPFAKGFRES----GQSRC 247
            ::...|.:|    |..|  .|.||||:||||||||::.:.:||:..|.||:|||||    ..|..
 Worm   133 NIYEISPVG----AHNQIGKFQFPETKFIAVTAYQSELVKQLKVQKNKFAQGFRESIKSNATSST 193

  Fly   248 KRKINDSPPPTQPEANQVDRSPVTSPLAKRLRLVEEFPQHHHHQSHHS-------VPMQRHYLLD 305
            ||.::.:...:.|::.              |.:..|...|...:....       :..|.:...|
 Worm   194 KRPLSTTSSNSSPDST--------------LSMSSENLGHTTKKGRGGGQEIGVLLTSQNYQSFD 244

  Fly   306 ALEANFYVPAPPPPAIEYARHIGGAYPSWAYTP 338
            .. :||....||.....||:|    ||...|.|
 Worm   245 QF-SNFSQAFPPNFQPSYAQH----YPIPDYQP 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	T-box_Drosocross-like	59..241	CDD:410332	65/183 (36%)
tbx-43	NP_001040883.1	T-box	5..183	CDD:459990	65/183 (36%)