Protein Alignment Doc3 and Tbx21

DIOPT Version :9

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001100513.1
• Gene: Tbx21 / 303496
• RGDID: 1308264
• Length: 528
• Species: Rattus norvegicus
• Alignment Length: 425
• Identity: 141/425 - (33%)
• Similarity: 192/425 - (45%)
• Gaps: 91/425 - (21%)

  Fly    30 PDPLCGLLPNFAGHFMPPPPPPQPTLP------GDVEAKLENNELWQQFHSIGTEMIITKCGRRM 88
            |||..||.|.         |.....||      |.:...|.|:.||.:|:...|||||||.||||
  Rat   110 PDPRAGLYPG---------PREDYALPAGLEVSGKLRVALSNHLLWSKFNQHQTEMIITKQGRRM 165

  Fly    89 FPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSP-QRMYLHPESPATGKH 152
            ||.:..:::|||..:.|.:.:::|.:....:::...:||..|.||...| .|:|:||:||.||.|
  Rat   166 FPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAH 230

  Fly   153 WQSQALLFSKVKLTNNTLDNNG---HIVLASMHKYQPRLHVIRTSDLGQIPWAPQQA-------F 207
            |..|.:.|.|:|||||...:|.   .|||.|:||||||||::..:| |:    |:.|       |
  Rat   231 WMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVND-GE----PEAACSANTHIF 290

  Fly   208 IFPETEFIAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKINDSPPPTQPEANQVDRSPVTS 272
            .|.||:|||||||||..||:||||||||||||||:.:|.........|.|..|....:...|.:.
  Rat   291 TFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSVPSPPGPNCQLLGGDPYSP 355

  Fly   273 PLAKRLRLVEEF-------PQHHHHQSHH-SVPMQRHYLLDALEANF--------YVPAPPPPAI 321
            .|:.:..:...|       |:....||:. ..|.:..|     |..|        ::|:.|...:
  Rat   356 LLSNQYPVSSRFYPDLPGQPKDMVSQSYWLGTPREPSY-----ETEFRAVSVKPTFLPSAPGTTV 415

  Fly   322 EYAR-----HIGGAYPSWAYTPP--SPASSV-------------SSSSAGSTS------------ 354
            .|.|     ..|..:|.....||  |||...             ||...||.|
  Rat   416 PYYRGPDVLAPGAGWPMAPQYPPKMSPAGWFRTMRTLPMDPGLGSSEEQGSPSLWTEVTSLQPEP 480

  Fly   355 -----GESAADREADADADTFVDVVGTAPAAPPPP 384
                 ||....|...:...:..|  .::||..|.|
  Rat   481 SDSGLGEGDTKRRRISPYPSSGD--SSSPAGAPSP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	93/197 (47%)
Tbx21	NP_001100513.1	T-box	138..324	CDD:279278	91/190 (48%)
		T-box_assoc	<392..518	CDD:292794	27/129 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840