Protein Alignment Doc3 and Tbx4

DIOPT Version :10

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_006247098.1
• Gene: Tbx4 / 303399
• RGDID: 1309057
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 460
• Identity: 155/460 - (33%)
• Similarity: 217/460 - (47%)
• Gaps: 112/460 - (24%)

  Fly    28 RLPDPLCGLLPNFAGHFMPPPPPPQPTLPG-----------------------------DVEAKL 63
            |.|.|..|...|.....:|.|....|.|.|                             :::..|
  Rat    15 RAPGPALGETSNSNNTNVPEPALATPGLSGTALSSPPGQGADVAAAAAAAAAAAEQTIENIKVGL 79

  Fly    64 ENNELWQQFHSIGTEMIITKCGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVP 128
            ...|||::||..||||||||.|||||||.:|.::|:..:..|.:|:::||..|.||||..::|:.
  Rat    80 HEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMV 144

  Fly   129 AGGAEPQSPQRMYLHPESPATGKHWQSQALLFSKVKLTNNTLDNNGHIVLASMHKYQPRLHVIRT 193
            ||.|||..|.|:|:||:|||||.||..|.:.|.|:|||||.||..|||:|.||||||||||:::
  Rat   145 AGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK- 208

  Fly   194 SDLGQIPWAPQQAF---IFPETEFIAVTAYQNDRITKLKIDNNPFAKGFRESGQS-----RCKRK 250
            :|......:...||   :||||.||:||:|||.:||:|||:|||||||||.|..|     |.:.|
  Rat   209 ADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSK 273

  Fly   251 ----INDSPPPTQPEANQVDRSPVTSPLAKRLRLVEEFPQHHHHQS------------------- 292
                |:.|....:..::|:...|..||    |....:..||:.:::
  Rat   274 EYPVISKSIMRQRLVSSQLSAKPDVSP----LHSTHQALQHYQYENGAHMQFAAAEPQDLPLNTF 334

  Fly   293 ---------------------HHSVPMQRHYL--LDALEANFYVPAPPPPAIEYARHIGGAYPSW 334
                                 |..:|.:|.||  ..::..:.|..:|||    |.:.:  ..||:
  Rat   335 PTQRDSSLFYHCLKRRADSARHLDLPCKRSYLETPSSVGDDHYFRSPPP----YDQQM--LSPSY 393

  Fly   335 AYTPPSPASSVSSSSAGSTSGESAADREADADADTFVDVVGTAPAAPPPPSPPVPATATAPASSS 399
            ........:.:.|||....:|.||.|           |:       ||||......|:.:|.:|.
  Rat   394 CSEVTPREACMYSSSGPEIAGVSAVD-----------DL-------PPPPLSCNMWTSVSPYTSY 440

  Fly   400 SDPTM 404
            |..||
  Rat   441 SVQTM 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	T-box_Drosocross-like	59..241	CDD:410332	101/184 (55%)
Tbx4	XP_006247098.1	T-box_TBX4_5-like	75..259	CDD:410315	101/184 (55%)