Protein Alignment Doc3 and tbx4

DIOPT Version :9

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_570989.2
• Gene: tbx4 / 30070
• ZFINID: ZDB-GENE-991124-5
• Length: 543
• Species: Danio rerio
• Alignment Length: 484
• Identity: 160/484 - (33%)
• Similarity: 222/484 - (45%)
• Gaps: 141/484 - (29%)

  Fly    37 LPNFAGHFMPPPPP--PQPTLPG----DVEAKLENNELWQQFHSIGTEMIITKCGRRMFPSMRVS 95
            |.:.:.|...|..|  ||...|.    :::..|.:.|||::||..||||||||.|||||||.:|.
Zfish    25 LASDSSHLGLPTTPSNPQNNEPDQSIENIKVVLHDRELWKKFHEAGTEMIITKAGRRMFPSYKVK 89

  Fly    96 LSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPESPATGKHWQSQALLF 160
            ::|:..:..|.:|.::||..|.||||..::|:.||.|||..|.|:|:||:|||||.||..|.:.|
Zfish    90 VTGMNPKTKYILLTDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSF 154

  Fly   161 SKVKLTNNTLDNNGHIVLASMHKYQPRLHVIRTSDLGQIPWAPQQAF----------IFPETEFI 215
            .|:|||||.||..|||:|.||||||||||:::..:        ..||          :|.||.||
Zfish   155 QKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADE--------NNAFGSKNTAYCTHVFHETAFI 211

  Fly   216 AVTAYQNDRITKLKIDNNPFAKGFRESGQ-----SRCKRKINDSPPPTQPEANQVDRSPVTS--P 273
            :||:|||.:||:|||:|||||||||.|.:     ||.:.|  |.|..::   |.|.:..::|  .
Zfish   212 SVTSYQNHKITQLKIENNPFAKGFRGSDEGDLRVSRLQGK--DYPVISK---NMVRQRLISSHGH 271

  Fly   274 LAKRLR--LVEEFPQ-HHHHQSHHSVPM------------------------------------- 298
            |:.:|.  ::...|| ..|:|....||:
Zfish   272 LSGKLSAGVLSSHPQVLSHYQYDSGVPLPNSDSQEALSNSFTSSREPSLLYHCFKHRDNPRHLEL 336

  Fly   299 --QRHYL---LDALEANFYVPAPP---PPAIEY--------ARHI----------GGAY------ 331
              :|.||   ..|:....|..:||   .|.:.:        :|..          |||.
Zfish   337 GCKRPYLDTTSSAVSEEHYFRSPPSYDSPLLSHPYCNEALGSREACMYGGLEGEGGGAVGTDDLP 401

  Fly   332 -PS-----WAYTPPSP--------ASSVSSSSAGSTSGESAADREADADADTFVDVVGTAPAAP- 381
             ||     ||...|.|        |......:|...|..|||..           |...:|:..
Zfish   402 APSLNCNMWASVQPYPRYGMQTVEAMQYQPFTAHFNSTASAASM-----------VSHHSPSMQR 455

  Fly   382 PPPSPPVPATAT-------APASSSSDPT 403
            |.|:||...|.|       .|:|:|:.|:
Zfish   456 PHPTPPDLVTFTTQRVLPPTPSSASTSPS 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	101/201 (50%)
tbx4	NP_570989.2	TBOX	52..240	CDD:238106	101/195 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910