Protein Alignment Doc3 and Tbx5

DIOPT Version :9

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_006530342.1
• Gene: Tbx5 / 21388
• MGIID: 102541
• Length: 537
• Species: Mus musculus
• Alignment Length: 424
• Identity: 154/424 - (36%)
• Similarity: 207/424 - (48%)
• Gaps: 66/424 - (15%)

  Fly    31 DPLCGLLPNFA-GHFMPPPPPPQP--TLPG--DVEAKLENNELWQQFHSIGTEMIITKCGRRMFP 90
            |..|...|..| |.....|..||.  |..|  .::..|...|||.:||.:||||||||.||||||
Mouse    40 DRSCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFP 104

  Fly    91 SMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPESPATGKHWQS 155
            |.:|.::||..:..|.:|:::||..|.||||:.::|...|.|||..|.|:|:||:|||||.||..
Mouse   105 SYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMR 169

  Fly   156 QALLFSKVKLTNNTLDNNGHIVLASMHKYQPRLHVIRTSD---LGQIPWAPQQAF---IFPETEF 214
            |.:.|.|:|||||.||..|||:|.||||||||||:::..:   .|    :...||   :||||.|
Mouse   170 QLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFG----SKNTAFCTHVFPETAF 230

  Fly   215 IAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKR--KINDSPPPTQPEANQVDRSPVT---SPL 274
            ||||:|||.:||:|||:|||||||||.|......|  ::.....|..|.:..  |..||   ||.
Mouse   231 IAVTSYQNHKITQLKIENNPFAKGFRGSDDLELHRMSRMQSKEYPVVPRSTV--RHKVTSNHSPF 293

  Fly   275 AKRLRLV---EEFPQHHHHQSHHSVPMQRHYLLDALEANFYVPAPPPPAIEYARHIGGAY----- 331
            :...|.:   ......:..::..|.|.|     |.|        |||.....|:.....|
Mouse   294 SSETRALSTSSNLGSQYQCENGVSGPSQ-----DLL--------PPPNPYPLAQEHSQIYHCTKR 345

  Fly   332 -------------PSWAYTPPSPASSVSSSSAGSTSGESAADREADADADTFVDVVGTAPAAPPP 383
                         ..:..|.||...:...|......|.|.:.|...|.....:      .|:..|
Mouse   346 KDEECSSTEHPYKKPYMETSPSEEDTFYRSGYPQQQGLSTSYRTESAQRQACM------YASSAP 404

  Fly   384 PSPPVPATATAPASSSSDPTMAKPKRSSFSISDI 417
            ||.|||  :....|.::.|:|  |..||.:::.:
Mouse   405 PSEPVP--SLEDISCNTWPSM--PSYSSCTVTTV 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	104/192 (54%)
Tbx5	XP_006530342.1	TBOX	72..260	CDD:238106	104/191 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910