Protein Alignment Doc3 and Tbx3

DIOPT Version :9

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_035665.2
• Gene: Tbx3 / 21386
• MGIID: 98495
• Length: 741
• Species: Mus musculus
• Alignment Length: 478
• Identity: 163/478 - (34%)
• Similarity: 231/478 - (48%)
• Gaps: 107/478 - (22%)

  Fly     2 LTLP--NIADLRLQQQIAQEIYRQQI-MQRLPDPLCGLLPNFAGHFMP-PPPPPQPTLPGDVEAK 62
            ||||  ..|.|.|...:|:.|..|.: ......|...|.|.  .|..| ....|:..:..|.:..
Mouse    44 LTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQ--AHLRPLKTMEPEEDVEDDPKVH 106

  Fly    63 LENNELWQQFHSIGTEMIITKCGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWV 127
            ||..|||.|||..||||:|||.||||||..:|..|||:::|.|.:|::::...||||||..|:|:
Mouse   107 LEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWM 171

  Fly   128 PAGGAEPQSPQRMYLHPESPATGKHWQSQALLFSKVKLTNNTLDNNG------------------ 174
            .||.|:|:.|:|||:||:|||||:.|.|:.:.|.|:|||||..|.:|
Mouse   172 VAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSF 236

  Fly   175 --HIVLASMHKYQPRLHVIRTSDLGQIPWAPQQAFIFPETEFIAVTAYQNDRITKLKIDNNPFAK 237
              ..:|.||||||||.|::|.:|:.::|::..:.::|||||||||||||||:||:||||||||||
Mouse   237 GTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAK 301

  Fly   238 GFRESGQSRCKRKINDSPPPTQPEANQVDRSPVTSPLAKRLRLVEEFPQHHHHQSHHSVPMQRHY 302
            |||::|..|.::                 |..:|   .:.:|:.||  :|....|..|...|..:
Mouse   302 GFRDTGNGRREK-----------------RKQLT---LQSMRVFEE--RHKKETSDESSSEQAAF 344

  Fly   303 LLDALEANFYVPAPPPP-AIEYARHIGGAYPSWAYTPPSPASSVSSSSAG-----------STSG 355
                   |.:..|..|. :|....::....||.|   .|.|.:.|....|           :|:.
Mouse   345 -------NCFAQASSPAVSIVGTSNLKDLCPSEA---ESDAEAESKEEHGPEACDAAKISTTTAE 399

  Fly   356 ESAADREADAD-ADTFVDVVGTAPAAP------------PPPSPPVPATATA------------- 394
            |...|:.:.|. |..|       ||.|            .|.|...|||.::
Mouse   400 EPGRDKGSPATRAQLF-------PAEPSRARDTARLDKASPDSRHSPATISSSTRVPGADERRSP 457

  Fly   395 ----PASSSSDPTMAKPKRSSFS 413
                |.::..|...|.|.:.:|:
Mouse   458 GREGPVATKVDEARAIPAKDAFA 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	107/206 (52%)
Tbx3	NP_035665.2	T-box	105..305	CDD:366363	104/199 (52%)
		TBX	323..402	CDD:372213	20/90 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	369..469		21/109 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810