Protein Alignment Doc3 and Tbx15

DIOPT Version :9

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_033349.2
• Gene: Tbx15 / 21384
• MGIID: 1277234
• Length: 602
• Species: Mus musculus
• Alignment Length: 478
• Identity: 154/478 - (32%)
• Similarity: 215/478 - (44%)
• Gaps: 133/478 - (27%)

  Fly    48 PPPPQPTLPGDVEAKLENNELWQQFHSIGTEMIITKCGRRMFPSMRVSLSGLEEEASYCVLLEMV 112
            |.|...:...:::.:|:..:||::||.|||||||||.||||||:|||.::||:....|.:.:::|
Mouse   102 PVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIV 166

  Fly   113 PIGDCRYK--FSGSQWVPAGGAEPQSPQRMYLHPESPATGKHWQSQALLFSKVKLTNNTLDNNGH 175
            |:.:.||:  :..|:|:.||.|:...|.|:|:||:|.|:|..|..|.:.|.|:|||||.||:.||
Mouse   167 PVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGH 231

  Fly   176 IVLASMHKYQPRLHVIR---TSDLGQIPWAP----QQAFIFPETEFIAVTAYQNDRITKLKIDNN 233
            |:|.||||||||:||||   :|||......|    .:.|.||||.|..||||||.:||:||||.|
Mouse   232 IILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRN 296

  Fly   234 PFAKGFRESGQSRC-KRKINDS-----PP-----------------------PT-------QPEA 262
            |||||||:||::|. ...|.::     ||                       ||       .|.|
Mouse   297 PFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSA 361

  Fly   263 NQVDRSPVTSPLAKRLRLVEEFPQHHHHQSHHSVPMQRHYLLDALEANFYVPAPPPPAIEYARHI 327
            :....||..||           |..|...:..:|..:...|.: |..:.|.|.        ||..
Mouse   362 SSHLLSPSCSP-----------PTFHLAPNTFNVGCRESQLCN-LNLSDYPPC--------ARSN 406

  Fly   328 GGAYPSWAYTPPSPASSVSSSSAGSTSGESAADREADADADTFVD--VVGTAPAAPPPPSPPVPA 390
            ..|..|:.....|..:.:.|.:|.:|.           .::||:.  ........|.|||.|..:
Mouse   407 MAALQSYPGLSDSGYNRLQSGTASATQ-----------PSETFMPQRTPSLISGIPTPPSLPSNS 460

  Fly   391 TATA---------------------PASSSSDPTM------------------------------ 404
            ...|                     .|||||.|.|
Mouse   461 KMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTS 525

  Fly   405 ----AKPKRSSFSISDILGTSSS 423
                |.|::.|.|.|.:|.:|.|
Mouse   526 PRLAASPEKLSASQSTLLCSSPS 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	102/195 (52%)
Tbx15	NP_033349.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..95
		TBOX	113..308	CDD:238106	102/194 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..369		5/30 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..444		5/29 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910