Protein Alignment Doc3 and Tbx10

DIOPT Version :9

• Sequence 1: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001001320.1
• Gene: Tbx10 / 109575
• MGIID: 1261436
• Length: 385
• Species: Mus musculus
• Alignment Length: 397
• Identity: 135/397 - (34%)
• Similarity: 186/397 - (46%)
• Gaps: 70/397 - (17%)

  Fly    21 YRQQIMQRLPDPLCGLLPNFAGHFMPPPPPPQPTLPGDVEAKLENNELWQQFHSIGTEMIITKCG 85
            :..::..|.|...|.:.........|....|:......|..:||...||::|:.:|||||:||.|
Mouse    27 WESRLGTRFPSGSCTMSTEAQAMAEPTGQGPKNPRVSSVMVQLEMKPLWEEFNQLGTEMIVTKAG 91

  Fly    86 RRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYK--FSGSQWVPAGGAEPQSPQRMYLHPESPA 148
            |||||:.:|.:.|::..|.|.:|::.:|:.|.||:  |..|.|:.||.|:|.:|.|::.||:|||
Mouse    92 RRMFPTFQVKILGMDTLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPA 156

  Fly   149 TGKHWQSQALLFSKVKLTNNTLDNNGHIVLASMHKYQPRLHVI---RTSDLGQIPWAPQQAFIFP 210
            .|..|..|.:.|.|:|||||.:|:||||:|.|||:||||.||:   ...|..:......::|:|.
Mouse   157 KGAQWMRQIVSFDKLKLTNNLMDDNGHIILNSMHRYQPRFHVVFVDPRKDSARYAQENFKSFVFT 221

  Fly   211 ETEFIAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKINDSPPPT-QPEANQVDRSPVT-SP 273
            ||:|.|||||||.|||:|||.:|||||||||:..        ||.|.| :|..:...||..: ||
Mouse   222 ETQFTAVTAYQNHRITQLKIASNPFAKGFREADP--------DSWPVTPRPLLSIPARSRSSLSP 278

  Fly   274 LAKRLRLVEEFPQHHHHQSHHSVPMQRHYLLDALEANFYVPAPP---PPAIEYARHIGGAYPSWA 335
            ...:.....|........|....|.|.|        |..:|||.   .||..........||.
Mouse   279 CLLKGSAEREKDTSKASASSSRTPTQPH--------NQLLPAPDVLLAPATYRPLPYQNLYPG-- 333

  Fly   336 YTPPSPASSVSSSSAGSTSGESAADREADADADTFVDVVGTAPAAPPPPS--PPVPATATAPASS 398
                      |.|.||                              ||.:  .|.|....:.|..
Mouse   334 ----------SPSRAG------------------------------PPRARLAPYPLPNISTAGD 358

  Fly   399 SSDPTMA 405
            ..|||:|
Mouse   359 QEDPTLA 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	95/191 (50%)
Tbx10	NP_001001320.1	TBOX	67..254	CDD:238106	94/186 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..310		6/34 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..359		11/72 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910