DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5087 and GAS7

DIOPT Version :9

Sequence 1:	NP_648279.1	Gene:	CG5087 / 39035	FlyBaseID:	FBgn0035953	Length:	1078	Species:	Drosophila melanogaster
Sequence 2:	NP_958839.1	Gene:	GAS7 / 8522	HGNCID:	4169	Length:	476	Species:	Homo sapiens

Alignment Length:	132	Identity:	33/132 - (25%)
Similarity:	56/132 - (42%)	Gaps:	31/132 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ASFLEQTKAARE-ERALEKRREQAAILL----QSTLKGYAARRK--------------YQKRIIL 53
            ||..:..||..| :|.||.:.:|..|.|    :..:|  .||||              |.:....
Human   334 ASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIK--KARRKSTQAGDDLMRCVDLYNQAQSK 396

  Fly    54 DFDAMFTENHDDKDAELELVASNVYPVLRRYL---TQIR--LDKSDVRARERLERICRYIIKAME 113
            .|:.|.|...:.:..|:|.|     .::|::|   ||:|  .|..:....|.::::.|.:..|.:
Human   397 WFEEMVTTTLELERLEVERV-----EMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 456

  Fly   114 SE 115
            .|
Human   457 RE 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	HECTc	694..1076	CDD:238033
CG5087	NP_648279.1	HECTc	718..1075	CDD:214523
GAS7	NP_958839.1	SH3_GAS7	5..57	CDD:212763
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	100..171
		WW_FCH_linker	109..201	CDD:374680
		F-BAR_GAS7	214..446	CDD:153333	30/118 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900