Protein Alignment CG5087 and UPL1

DIOPT Version :10

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: NP_001185245.1
• Gene: UPL1 / 842036
• AraportID: AT1G55860
• Length: 3681
• Species: Arabidopsis thaliana
• Alignment Length: 1270
• Identity: 289/1270 - (22%)
• Similarity: 486/1270 - (38%)
• Gaps: 366/1270 - (28%)

  Fly     5 NQKASFLEQTKAAREERALEKRREQAAILLQSTLKGYAARRKYQKRIILDFDAMFTENHDDKDAE 69
            |.:.|.:|.|:..|.:..:|          :.:|.|.|..       :...|..|.|...: |..
plant  2576 NNELSSMEATENVRNDEQVE----------EGSLDGRAPE-------VNAIDPTFLEALPE-DLR 2622

  Fly    70 LELVAS----NVYP----------VLRRYLTQIRLD-KSDVRARERLERICRYIIKAMESENTKL 119
            .|::||    :|.|          :...:|..:..| :::|.|::|.:|    :::..:.:...:
plant  2623 AEVLASQQAQSVQPPTYEPPPVDDIDPEFLAALPPDIQTEVLAQQRAQR----MVQQSQGQAVDM 2683

  Fly   120 SYAALCLFKERSLPWIAHIKILLTN---CLTLLPE------------------------------ 151
            ..|::.    .:||.....::|||:   .|..||.
plant  2684 DNASII----ATLPADLREEVLLTSSEAVLAALPSPLLAEAQMLRDRAMSHYQARSSVFGSSHRL 2744

  Fly   152 ----------------------------------LK-PENHADSLSLALFLHTLVVFTAPKSWAI 181
                                              || .|...|.|..|..|.:|:        .:
plant  2745 NNRRNGLGYNRLTGMDRGVGVTIGQRAVSSSADGLKVKEIEGDPLVNADALKSLI--------RL 2801

  Fly   182 LRNAQFEKLQP----AMQKICCNIQGHLVQHDFYKIMRLVLIRGTVREELSVKPVTLVAIITL-- 240
            ||.|     ||    .:|::..|    |..|.|.:...:.|:...:|.|:...|..|.  ||.
plant  2802 LRLA-----QPLGKGLLQRLLLN----LCAHSFTRANLVQLLLDMIRPEMETSPSELA--ITNPQ 2855

  Fly   241 ----CLRPLIDGNFSRNLLAKFLSEILS-VPALIYHL-----------QQSVPQCLEQFSSMGLL 289
                |...::.|.          |::|: :|.|::..           ..:|...|..|.| .||
plant  2856 RLYGCQSNVVYGR----------SQLLNGLPPLVFRRVLEVLTYLATNHSAVADMLFYFDS-SLL 2909

  Fly   290 KKALSISGDVQWFEEFGTSMPGTKSL-----AFLGNIVNLFNIDGQGESKELAYPLLTETTT--- 346
            .:..|..|     :|..|.:..::.|     .||               |.|..|.|.::|:
plant  2910 SQLSSRKG-----KEKVTHVTDSRDLEIPLVVFL---------------KLLNRPQLLQSTSHLG 2954

  Fly   347 ---SLLELIPNTVTTKGVFTQWHELLGWHTPG---PEPAQNQNV-----ALIKKQFHMLWDHRCI 400
               .||:::        |:|....:.|| :|.   ||..:|:.|     :..:|...
plant  2955 LVMGLLQVV--------VYTAASRIEGW-SPSSGVPEKLENKPVGEEASSETRKDAE-------- 3002

  Fly   401 KLLLGDLLKQINLNYER---------IEFQSPQQPSISNLLRRALERSSTRGVNLMGVASSKQSK 456
                .:|:.:.:|:..|         |..|.||....:..:....|..|.:..:|.|....|.:.
plant  3003 ----SELVGEADLSVARRKNCAEIYNIFLQLPQSDLCNLCILLGYEGLSDKIYSLAGEVLKKLAA 3063

  Fly   457 QQ--WRKLDSAEVVQV-SRICGMYYAALNTL-SQMKLDILTGICYSDNVLYDIWLLITSLGP--- 514
            ..  .||..:.|:.:: |.:.......|.|| |:.|:...||.....::|..:.:|.:...|
plant  3064 VDVAHRKFFTKELSELASSLSSSTVRELATLSSKQKMSRSTGSMAGASILRVLQVLSSLTSPIDE 3128

  Fly   515 -NCGMKEYLELLKSETN-LQKPQTAMLMLF-----CDCMTHYVTILDEHEMYTEQNPFKLNDYVL 572
             |.|.:...|  :.|.| :|:...|:..|:     |..||...  ||.....:..||   .|:||
plant  3129 SNVGTERETE--QEEQNIMQRLNVALEPLWHELSQCISMTELQ--LDHTAAASNINP---GDHVL 3186

  Fly   573 LTYFLNNILYKLINDNLLAGAKNIVQHPVFLSLHTLMLCLYRRDCRRPFTP-----PKHWLIPEV 632
            ..         ....:|..|.:.::  |:..:...|        |.:..||     ..:....||
plant  3187 GI---------SPTSSLSPGTQRLL--PLIEAFFVL--------CEKIQTPSMLQQDTNVTAGEV 3232

  Fly   633 KPS---------------------TFINDLEKAKR--------------NAMLLLAKMPHIIPHE 662
            |.|                     ||....||.:|              .::.::.|.|.:|..:
plant  3233 KESSAHGSSSKTSVDSQKKTDGSVTFSKFAEKHRRLLNSFIRQNPSLLEKSLSMMLKAPRLIDFD 3297

  Fly   663 DRVKLFRKFV--QNEKAVMGLTESACASPRSALIVIHRDRIVEDGYRQLAAQPTQALKGVIRVRF 725
            ::...||..:  |:::.:.|          ...|.:.|..::||.|.||..:..|.|||.:.|:|
plant  3298 NKKAYFRSRIRHQHDQHISG----------PLRISVRRAYVLEDSYNQLRMRSPQDLKGRLNVQF 3352

  Fly   726 INQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTT-SDQRLYPSPISYVQDNHLELFEFVG 789
               ||  |.|||..|:.:|:.:...:.:||....||.|. :|....|:|.|..|..||..|:|||
plant  3353 ---QG--EEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDATFQPNPNSVYQTEHLSYFKFVG 3412

  Fly   790 RMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCMDELPSLDNELYRSLTFIKHYKQDVSD-L 853
            ||:.||:::|.::||.|...|...:||  .:..|   .::.::|.:.|::|.::  .:.|||| |
plant  3413 RMVAKALFDGQLLDVYFTRSFYKHILG--VKVTY---HDIEAVDPDYYKNLKWL--LENDVSDIL 3470

  Fly   854 NLTFSVDQD-------VMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNR 911
            :||||:|.|       ...::....|.|||:...|.:..|..|:..:|...:...||.|..||..
plant  3471 DLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVAGHILTNAIRPQINAFLE 3535

  Fly   912 GFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTE 976
            ||..::..|.:|:|:..||:.|||| ...:|..||:.:|. |..:.....|:.|.|::: |.|::
plant  3536 GFNELIPRELVSIFNDKELELLISG-LPEIDFDDLKANTE-YTSYTAGSPVIHWFWEVV-KAFSK 3597

  Fly   977 EERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLP 1041
            |:...||:|||..||.||.||..|:.....:.:::.                   :......|||
plant  3598 EDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIH-------------------KAYGAPERLP 3643

  Fly  1042 TSSTCFNLLKLPNYQKKSTLRDKLRYAV-SSNTGF 1075
            ::.||||.|.||.||.|..|:::|..|: .::.||
plant  3644 SAHTCFNQLDLPEYQSKEQLQERLLLAIHEASEGF 3678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	IQCD	20..50	CDD:467745	4/29 (14%)
		HECTc	694..1076	CDD:238033	128/392 (33%)
UPL1	NP_001185245.1	DUF908	88..357	CDD:428721
		DUF913	418..763	CDD:461803
		UBA_atUPL1_2_like	1273..1310	CDD:270512
		UBM	2603..2631	CDD:464159	8/35 (23%)
		UBM	2641..2672	CDD:464159	6/34 (18%)
		HECTc	3319..3679	CDD:238033	128/394 (32%)