Protein Alignment CG5087 and ube3a

DIOPT Version :10

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: NP_001007319.1
• Gene: ube3a / 792398
• ZFINID: ZDB-GENE-041114-190
• Length: 857
• Species: Danio rerio
• Alignment Length: 730
• Identity: 172/730 - (23%)
• Similarity: 305/730 - (41%)
• Gaps: 156/730 - (21%)

  Fly   437 ERSSTRGVNLMGVASSKQSKQQWRKLDSAEV-VQVSRICGMYYAALNTLSQMKLDILTGICY-SD 499
            |.|::.|      ..|...:...:||...|| |.:..:..:|...|:. .:::...|..:.| |.
Zfish   190 EASASSG------DGSSHGENNVQKLGPVEVSVDIDAVRRVYDRLLSN-EKIEAAFLNALVYLSP 247

  Fly   500 NVLYDI-WLLITSLGPNCGMKEYLE---LLKSETNLQKPQTAMLML--FCDCMTH---------- 548
            ||..|: :..:.:..||     ||.   ::...:||..|:...:.|  ||..|:.
Zfish   248 NVECDLTYHNVYAADPN-----YLNVFIIVMENSNLHSPEYLEIALPQFCKAMSKLPLPALAKLA 307

  Fly   549 -----------------------YVTILDEHEMYTEQNPFKLNDYVL-------LTYFLNNILYK 583
                                   |..|.:|   ::..|....:|.|:       :.|:.|.:...
Zfish   308 RLWSQYGVDQIRRLVETFQQLITYTVISNE---FSSDNLVNEDDGVVAATKCLKIVYYANVLGGD 369

  Fly   584 LINDN-------------------LLAGAKNIVQHPVFLSLHTLMLCLYRRDCRRPFTP------ 623
            |..|:                   ||...:...:.|....|.|.| .:...|||:|..|
Zfish   370 LDTDHNEEDDDEPIPESSELTLQELLGEERRNKKGPRVDPLETEM-GIRASDCRKPLIPFEEFIN 433

  Fly   624 -PKHWLIPEVKPSTFINDLEKAKRNAM----LLLAKMPHI-IPHEDRVKLFRKFVQNEKAVMGLT 682
             |.:.::...|..||.....::|.:.|    :|.|...:: :.:::|::::.:  :...|:..|.
Zfish   434 EPLNEVLEMDKDYTFFKVETESKFSFMTCPFILNAVTKNLGLYYDNRIRMYSE--RRITALYSLV 496

  Fly   683 ESACASPRSALIVIHRDRIVEDG---YRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKE 744
            :....:|...| .:.||.|::|.   ...:|.:....||..:.|.|..:|     |:|:.||.||
Zfish   497 QGQQLNPYLRL-KVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQ-----GVDEGGVSKE 555

  Fly   745 FLEETIKKVFDPSLNLFKTTSDQRLY-PSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFAS 808
            |.:..::::|:|.:.:|......:|: .:|.|:..:..   |..:|.:||.|:|...::||.|..
Zfish   556 FFQLVVEEIFNPDIGMFTYDESTKLFWFNPSSFENEGQ---FTLIGIVLGLAIYNNCILDVHFPM 617

  Fly   809 FFLSQLLGQTQQALYSCMDELPSLDNELYRSLTFIKHYKQDV-SDLNLTFSVDQ-DVMGKIVTLA 871
            ....:|:|:.     ....:|......|::||..:..|:.:| .|:.:||.:.| |:.|..:...
Zfish   618 VIYRKLMGKK-----GTFRDLADSHPVLFQSLKDLMEYEGNVEEDMMITFQISQTDLFGNPLMYD 677

  Fly   872 L-HPGGKARVVNDHNK---LVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLS-LFSPPELQ 931
            | ..|.|..|.|::.|   .:|..||    :|..:.:|..||.|||..:.|...|. ||.|.|::
Zfish   678 LKESGDKIPVTNENRKDFVALYAEYM----LNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIE 738

  Fly   932 RLISGDTSPLDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLG 996
            .||.|..: ||.:.|::.|.|.||::...:::...|:.: ..|.:|:::|||:|.|...:.|:.|
Zfish   739 LLICGSRN-LDFQALEESTEYDGGYNKDSRIIRDFWETV-HSFEQEKKRLFLQFTTGTDRAPVGG 801

  Fly   997 FAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDP-LNRLPTSSTCFNLLKLPNYQKKST 1060
            ...|:                           ..|.|..| .:|||||.||||:|.||.|.....
Zfish   802 LGKLK---------------------------MIIAKNGPDSDRLPTSHTCFNVLLLPEYSTVEK 839

  Fly  1061 LRDKLRYAVSSNTGF 1075
            |:::|..|::...||
Zfish   840 LKERLLKAITYAKGF 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	IQCD	20..50	CDD:467745
		HECTc	694..1076	CDD:238033	110/394 (28%)
ube3a	NP_001007319.1	AZUL	6..60	CDD:465173
		HECTc	505..855	CDD:238033	111/397 (28%)