Protein Alignment CG5087 and trip12

DIOPT Version :9

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: XP_005159283.1
• Gene: trip12 / 564866
• ZFINID: ZDB-GENE-041111-262
• Length: 2096
• Species: Danio rerio
• Alignment Length: 623
• Identity: 135/623 - (21%)
• Similarity: 234/623 - (37%)
• Gaps: 180/623 - (28%)

  Fly   552 ILDEHEMYTEQNPFKLNDYVLLTYFLNNI------LY------------KLINDNLLAGAKNIVQ 598
            |.|..|..|..:|..  :.:||...|::|      ||            :.||..|.|.|...:|
Zfish  1558 ICDPPEGITFDDPSM--EVILLLRVLHSISRYWFYLYDNAACKEIIPTGEFINSKLTAKANRQLQ 1620

  Fly   599 HPVFLSLHTLMLCLYRRDCRRPFTPPKHWLIPEVKPSTFINDLEKAKRNAMLLLAKMPHIIPHED 663
            .|:.:....                     ||     |::.:|.|.          .|...|.:.
Zfish  1621 DPLVIMTGN---------------------IP-----TWLTELGKT----------CPFFFPFDT 1649

  Fly   664 RVKLF------------RKFVQNEKAVMGLTESACASPR--SALIVIHRDRIVEDGYRQLAAQPT 714
            |..||            |....|.:.....::.:..:||  .....|:||.:::..  :...|..
Zfish  1650 RQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTINRDELLKQA--ESVMQDL 1712

  Fly   715 QALKGVIRVRFINQQGLHEAGIDQDGVFKEFL-----------------------------EETI 750
            .:.:.::.:::.|:.|   .|:   |..:||.                             :|..
Zfish  1713 GSSRAMLEIQYENEVG---TGL---GPTQEFYALVSQELQRADLGLWRGEEVTLSNPKVGSQEGT 1771

  Fly   751 KKVFDPSLNLFKTTSDQRLYPSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLL 815
            |.:|. |..||.....:...|:.|:.::..    |.|:|:::.||:.:..::|:|....|...:|
Zfish  1772 KYMFS-SRGLFAVPFGRTTKPAHIAKIKMK----FRFLGKLMAKAIMDFRLLDLPLGLPFYKWML 1831

  Fly   816 GQTQQALYSCMDELPSLDNELYRSLTFI-------KHYKQD---------------------VSD 852
             :.:.::.|  .:|.::|..:.:|:..:       |..:||                     |.|
Zfish  1832 -RHESSISS--HDLVNIDPGVAKSIQHLEDIIRQKKRIEQDRSHTRETLQQALESLNMNGCSVED 1893

  Fly   853 LNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSIV 917
            |.|.|:     :.....:.|..|||...|..||...|:..:.::.:|..:..|..:|..||.|:.
Zfish  1894 LGLDFT-----LPGFPNIELKKGGKDVPVTIHNLEDYLRLVVYWTLNEGVLRQFESFREGFESVF 1953

  Fly   918 NPEWLSLFSPPELQRLISGDTS-PLDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKL 981
            ....|..|.|.||.:|:.|..| ..|:|.|.:......|:....:.|.:|:::|: .|..|:::|
Zfish  1954 PLHHLQYFYPEELDQLLCGSKSESWDVKTLMECCRPDHGYTHDSRAVRFLFEVLS-SFDAEQQRL 2017

  Fly   982 FLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRK-----KDPLNRLP 1041
            ||:|||...:.|:.||..|.||.:|                        :||     ::|.:.||
Zfish  2018 FLQFVTGSPRLPVGGFRSLNPPLTI------------------------VRKTFESTENPDDFLP 2058

  Fly  1042 TSSTCFNLLKLPNYQKKSTLRDKLRYAV-SSNTGFELS 1078
            :..||.|.||||:|.....:|:||..|. .....|.||
Zfish  2059 SVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS 2096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	HECTc	694..1076	CDD:238033	100/445 (22%)
		HECTc	718..1075	CDD:214523	96/420 (23%)
trip12	XP_005159283.1	WWE	842..907	CDD:280915
		HECTc	1693..2094	CDD:238033	100/446 (22%)
		HECTc	1711..2090	CDD:214523	96/422 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900