Protein Alignment CG5087 and hectd2

DIOPT Version :9

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: XP_009304826.1
• Gene: hectd2 / 562999
• ZFINID: ZDB-GENE-100405-3
• Length: 756
• Species: Danio rerio
• Alignment Length: 860
• Identity: 190/860 - (22%)
• Similarity: 320/860 - (37%)
• Gaps: 220/860 - (25%)

  Fly   304 EFGTSMPGTKSLAFLGNIVNLFNIDGQGESKELAYPLLTETTTSLLELIPNTVTTKGVFTQWHEL 368
            |.|..:|    ....|:.::..|...:..|...:.||.......:.||.|       ::
Zfish    30 ERGPKLP----FPSYGSFISTLNHKRESGSHSFSSPLFLPAVKQVRELPP-------IY------ 77

  Fly   369 LGWHTPGPEPAQNQNVAL------IKKQFHMLWDHRCIKLLLGDLLKQINLNYERIEFQSPQQPS 427
                   |:..|...:::      :|.:|            :.:.:..|.....: |||..
Zfish    78 -------PDVRQKHRISIDVLPPEVKARF------------VSEPIIPIRTKTAK-EFQDD---- 118

  Fly   428 ISNLLRRALERSSTRG----------------VNLMGVASSKQSKQQWRKLDSAEVVQVSRICGM 476
                    :||::..|                :.|.| |..|::...:..::.:. :.:..:..:
Zfish   119 --------VERATISGDWKHVHDFYLTTFDSFLELNG-AFKKEANAPFNTIEDSG-INIKFVNIV 173

  Fly   477 YYAALNTLSQMKLDILTGICYSDNVLYDIWLLITSLGPNC--GMKEYLELLKSETNLQKPQTAML 539
            |.|.|:|.:..:..:|.||.   |.|...|     .||..  .::.|..|::   |.|....|..
Zfish   174 YDALLHTPADTQKSVLKGII---NSLLREW-----KGPRTKDDLRAYFVLVQ---NPQYTSPATY 227

  Fly   540 MLFCDCMTHYVTI--LDEHEM--YTEQNPFKLNDYVL--LTYFLNNILY---------------- 582
            :::...:.....:  .|.|.:  :.::.|.|....::  |..|:...|:
Zfish   228 VIYAHLLRQIAALAEADHHFLMHWFKKLPQKRFKQLVERLQLFITTRLFPAKPEELPPMAKCSWW 292

  Fly   583 -----KLINDNLLAGAKNIVQHPV--FLSLHTLML--CLYRRD---------------CRRPFTP 623
                 |::  :||..|.:|...|:  |...:.|.|  ..:..|               |:.||.
Zfish   293 IPSATKVL--SLLNAANSISSAPIIPFTDFYNLTLDHIDFMEDYHTWQVHGNSNRFTFCQFPFI- 354

  Fly   624 PKHWLIPEVKPSTFINDLEKAKRNAMLLLAKMPHI--IPHEDRVKLFRKFVQNEKAVMGLTESAC 686
                |...||.:....|.|:    .|:.:|:...:  :....||.:...|:.
Zfish   355 ----LSTVVKKAIIQRDSEQ----QMISMARQTLVDKVSRRQRVDMSLLFLN------------- 398

  Fly   687 ASPRSALIVIHRDRIVEDGYRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIK 751
                   |.:.|.::|.|...:|:.:... ||..::|.|:.     |||:|..|:.||:....|:
Zfish   399 -------IKVRRLQLVSDSLDELSRKRAD-LKKKLKVTFVG-----EAGLDMGGLTKEWFLLLIR 450

  Fly   752 KVFDPSLNLFKTTSDQRLYPSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLG 816
            ::|.....:|....:.:.|... |:..||:.| |..||.::|.|||..|.:|:.|......:||
Zfish   451 QIFHTDYGMFTYVKESQCYWFS-SWKCDNYSE-FRLVGALMGLAVYNSITLDIRFPPCVYKKLL- 512

  Fly   817 QTQQALYSC------------MDELPSLDNELYRSLTFIKHYKQDV-SDLNLTFSVDQDVMGKIV 868
              ...:..|            :|:|..:..:|...|..:..|:.:| .|...||.|.|:.:|.:.
Zfish   513 --TPPIVPCDLDTPVGMATLTLDDLQQIMPDLAHGLGELLSYEGNVEEDFYTTFQVFQEELGVVK 575

  Fly   869 TLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRL 933
            ...|.|||....|.:.|:..|:.....|.:|..|..|..||..||.|:.....|.|..|.|::.|
Zfish   576 AYNLKPGGDKIPVTNLNRKEYVQLYIDFLLNKSIYRQFAAFYHGFHSVCASNALMLLRPEEVEIL 640

  Fly   934 ISGDTSP-LDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGF 997
            :.|  || ||:..||:... |.|:..|...:...||::.. |..|.:|..|.|.|...:.|:.|.
Zfish   641 VCG--SPNLDMGSLQRVVQ-YEGYSKTDPTIRAFWDVVLA-FPLELQKKLLHFTTGSDRVPVGGM 701

  Fly   998 AHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSSTCFNLLKLPNYQKKSTLR 1062
            |.|.  |.|..::||.|                        .||.|.||||.:.||.|:.|..||
Zfish   702 ADLN--FKISKIDVSTD------------------------WLPVSHTCFNQICLPPYKSKKELR 740

  Fly  1063 DKLRYAVSSNTGFEL 1077
            .||..|:|:..||.|
Zfish   741 QKLTIAISNAEGFGL 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	HECTc	694..1076	CDD:238033	115/395 (29%)
		HECTc	718..1075	CDD:214523	108/370 (29%)
hectd2	XP_009304826.1	HECTc	397..754	CDD:238033	115/417 (28%)
		HECTc	420..753	CDD:214523	109/373 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900