Protein Alignment CG5087 and hyd

DIOPT Version :10

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: NP_001287262.1
• Gene: hyd / 41181
• FlyBaseID: FBgn0002431
• Length: 2887
• Species: Drosophila melanogaster
• Alignment Length: 1244
• Identity: 222/1244 - (17%)
• Similarity: 391/1244 - (31%)
• Gaps: 417/1244 - (33%)

  Fly    71 ELVASNVYPVLRRYLTQIRLDKSDVRA-----RERLERICRYIIKAMESENTKLSYAALCLFKER 130
            ||::...|.||....|.:::...:..|     .:||:....::...|:....:|.:.|
  Fly  1821 ELISILSYNVLNDIETSLKIQNDEAIAVQAFVEKRLKATWDWMFTVMDGTEAQLKFGA------- 1878

  Fly   131 SLPWIAHIKILLTNCLTLLPELKPENHADSLSLALFLHTLVVFTAPKSWAILRNAQFEKLQ---P 192
                      .|||       ....||.        ||.|.:           :||....|   |
  Fly  1879 ----------YLTN-------YTDPNHP--------LHPLNL-----------SAQASSSQTPAP 1907

  Fly   193 AMQKIC--CNIQGHLVQHDFYKIMRLVLIRGTVREELSVKPVTLVAIITLCLRPLIDGNFSRNLL 255
            |.....  .||.|...:.||:... |.|:|....|.....||..:..:
  Fly  1908 ATSSSVNGVNIMGSNSRRDFFTYC-LSLMRSHTSEHRDALPVLDITAL----------------- 1954

  Fly   256 AKFLSEILSVPALIYHLQQSVPQCLEQFSSMGLLKKALSISG----------------DVQWFEE 304
             :.::.:|.  |.:|:::          :..|...|..:|||                ::...||
  Fly  1955 -RHIAYVLD--AFVYYMR----------NDSGFYDKQDTISGRINNLSPMTESYDTDDELANLEE 2006

  Fly   305 F-------GTSMP----GTKSLAFLGNIVNLFNI-----DGQGESKELAYPL-----LTETTTSL 348
            |       .:|||    ||:..||.....:..::     :|.....::|.||     |.:..:..
  Fly  2007 FNADVQMSASSMPSGSQGTRRHAFFARSESTLSLGCSAPEGFELPLDMAMPLADKPHLLQPNSKR 2071

  Fly   349 LEL---IPNTVTTK-------------GVFTQWHELLGWH------------------------- 372
            .||   :|..|||.             .:|......||:.
  Fly  2072 QELFANLPLLVTTNANNSGATNDGDGGSIFDYTPTRLGFSNSLKRNERVYETVPIDSSKTGDGNV 2136

  Fly   373 TPGPEPAQNQN--VALIKKQ------FHMLWD------HRCIKLLLGDLLKQINLNYERIEFQSP 423
            |...|.:.:.|  |.|.|||      .|...|      .:.:.:...|.|...:.:.|.:....|
  Fly  2137 TNKAEGSTDSNIYVQLKKKQGSDDFKSHKEADGNQSKYEKVVLMETDDSLPSTSKSTEALMATRP 2201

  Fly   424 Q---QPSISNLLRRALER---------------SSTRGVNLMGVASSKQSK--QQWRKLDSAEVV 468
            :   .|:.:::......|               |.....:...:::::|:|  .|::|..|..::
  Fly  2202 EVIIAPNKASVSPATAARSVIVLAGGSCLKTIDSDINNYSASNLSTAEQAKCDTQYQKSTSDHLL 2266

  Fly   469 QVSRICGMYYAALNT--------LSQMKLDI-LTGICYSDNVLYDIWLLITSLGPNC-------- 516
            ........:|.:..:        ||:.||.: |.|..:.|    |:.:...|:.|..
  Fly  2267 LFPARGSQFYQSNFSELPSWNFLLSRWKLTLDLFGRVFMD----DVGMEHGSVLPELRGFPVKEM 2327

  Fly   517 -----------GMKEYLELLKSETNLQKPQTAMLMLFCDCMTHYVTILDEHEMYTEQNPFKLNDY 570
                       |.:..|.|.|.|.|   .::.::..|.:..|.:     .::....|.|...| .
  Fly  2328 RFRRHMEKLRNGQQRDLVLCKLERN---RESLIVQTFKELNTQF-----GNQSRRIQPPITFN-R 2383

  Fly   571 VLLTY--------FLNNILYKLINDNLLAGAK--NI------VQHPVFLSLHTLML--------- 610
            |.:|:        .:....|..|.:.|||.||  |:      ..|..::...:.:|
  Fly  2384 VKVTFKDEPGEGSGVARSFYTSIAEALLASAKIPNLESVQVGTNHSKYVVPFSSILRSRTVSGSS 2448

  Fly   611 ----CLYRRDCR------------------RPFTPPK----------------------HWLIPE 631
                .|.||...                  ||:|||.                      ..|.|:
  Fly  2449 RDQSTLQRRGSNSKILWRSARERKALNLDARPYTPPNSSDNATPESLNDHLSVHLQQIGERLYPK 2513

  Fly   632 VKPSTFINDLEKAKRNAMLLLAKMPHIIPHEDRVKLFRKFVQNEKAVMGLTESACASPRSALIVI 696
            :..   ||.....|...|||....|.::......:..|:.|.....::...:.:..|.:|
  Fly  2514 IHS---INQTHAPKITGMLLEIPTPQLLSVISSDETLRQKVNEAIEIITFKQKSETSAQS----- 2570

  Fly   697 HRDRIVEDGYRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLF 761
                          :||.::...|:                            :..|.|.:..||
  Fly  2571 --------------SQPKKSPSVVV----------------------------VDPVDDDNEPLF 2593

  Fly   762 KTTSDQRLYPSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCM 826
            .:...:..|.....:.....:..|..:||::|..:.:..::.:......|..:||:..:     .
  Fly  2594 YSPGKRGFYTPRQGFASFERINAFRNIGRLIGLCLLQNELLPLFLQRHVLKYILGRKIK-----F 2653

  Fly   827 DELPSLDNELYRSLTFI------KHYKQDVSDLNLTFSVD---QDVMGKIVTLALHPGGKARVVN 882
            .:|...|..||.|...|      |..::.::.:.|.|.:|   ::..|   ...|.|||:...|.
  Fly  2654 HDLAFFDPALYESFRQIIQNAQTKEGEETINRMELCFVIDLMKEEGCG---NRELIPGGRDVAVT 2715

  Fly   883 DHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKDLQ 947
            ..|...|:.....:.:.....:...|...|...::....:...:..:|:.|::| ...:::..|.
  Fly  2716 SSNIFEYVRRYTEYRLIKSQEKALEALKDGVFDVLPDNSMINLTAEDLRLLLNG-VGDINVSTLI 2779

  Fly   948 KHTHYYGGFHDTH--------QVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLL--GFAHLEP 1002
            .:|    .|:|..        :...|.|.|:.| ....||:..:.|.|.....|..  ||..| |
  Fly  2780 SYT----TFNDESSEGPDKLLKFKKWFWSIVEK-MNIMERQDLVYFWTGSPALPASEEGFQPL-P 2838

  Fly  1003 PFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSSTCFNLLKLPNYQKKSTLRDKLRY 1067
            ..:||   .:||                       :.|||::||.:.|.:|.|..||.||.|:..
  Fly  2839 SVTIR---PADD-----------------------SHLPTANTCISRLYIPLYSSKSILRSKMLM 2877

  Fly  1068 AV-SSNTGF 1075
            |: |.|.||
  Fly  2878 AIKSKNFGF 2886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	IQCD	20..50	CDD:467745
		HECTc	694..1076	CDD:238033	77/402 (19%)
hyd	NP_001287262.1	UBA_like_SF	150..196	CDD:473871
		UBR-box_UBR5	1211..1286	CDD:439073
		MDN1	<1551..>1724	CDD:444083
		PolyA	2498..2561	CDD:197769	11/65 (17%)
		HECTc	2589..2884	CDD:214523	69/335 (21%)