Protein Alignment CG5087 and Ube3c

DIOPT Version :9

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: XP_038964472.1
• Gene: Ube3c / 362294
• RGDID: 1559986
• Length: 1083
• Species: Rattus norvegicus
• Alignment Length: 1222
• Identity: 319/1222 - (26%)
• Similarity: 531/1222 - (43%)
• Gaps: 307/1222 - (25%)

  Fly     4 QNQKASFLEQTKAAREERALEKRREQAAILLQSTLKGYAARRKYQKRIILDFDAMFTENHDDKDA 68
            :.:|||.|.:|:..|.:|..|:||.:.|:::||.::||..|::          ..||:.     :
  Rat    22 KEEKASLLHRTQEERRKREEERRRLKNAVIIQSFIRGYRDRKQ----------QYFTQR-----S 71

  Fly    69 ELELVASNVYP--------------VLRRYLTQIRLDKSDVRARERLERICRY---IIKAMESEN 116
            ..:..|.:..|              ::|:.|...:..:...|.....:.:.::   .:|.::.
  Rat    72 AFDQCADSAQPGGTFRIADGPALTLLVRQLLFFYKQSEDSKRLIWLYQNLIKHSSLFVKQLDG-- 134

  Fly   117 TKLSYAALCLFKERSLPWIAHIKILLTNCLTLLPELKPENHADSLSLALFLHTLVVFTAPKSW-A 180
               |....|||:         :|.|::.|..||.....    |||::||.:..|.||::..:: .
  Rat   135 ---SERLTCLFQ---------LKRLMSLCCRLLQNCSD----DSLNVALPMRMLEVFSSENTYLP 183

  Fly   181 ILRNAQFEKLQPAMQKICCNIQGHLVQHDFYKIMRLVLIRGTVREELSVKPVTLV----AIITLC 241
            :|:::.:      :..:...|..::|...:|:.:.| ||...:...:....::.|    .::...
  Rat   184 VLQDSSY------VVSVIEQILHYMVHSGYYRSLYL-LINSKLPSSIEYSDLSRVPMAKTLLENV 241

  Fly   242 LRPLIDGNFS---------RNLLAKFLSEILSVPAL--IYHL--------QQSVPQCLEQFSSMG 287
            |:||   :|:         ..:.:.|..|.|..|..  |||.        |...|  .|.|.:..
  Rat   242 LKPL---HFTYSSCPEGARHQVFSAFTEEFLGAPFTDQIYHFIIPALADTQTVFP--YEPFLNAL 301

  Fly   288 LLKKALSI--SGDVQWFEEFGTSMPGTKSLAFLGNIVNLFNIDGQGESKELAYPLLTETTTSLLE 350
            ||.::.|.  |..|.|...|        .|....|.:...:.||.     |.|..:.:|..|.|.
  Rat   302 LLLESRSSKRSSGVPWLFYF--------VLTIGENYLGALSEDGL-----LVYLRVLQTFLSQLP 353

  Fly   351 LIPNTVTTKGVFTQWHELLGWHTPGPEPAQNQNVALIKKQFHMLWDHRCIKLLLGDLLKQINLNY 415
            ..|..|..                 |:|..:..                            :.|.
  Rat   354 ASPTGVGR-----------------PDPTSDSE----------------------------DDNE 373

  Fly   416 ERIEFQSPQQPSIS------NLLRRALERSSTRG-VNLMGVASSKQSKQQWRKLDSAEV-VQVSR 472
            |..:..||:...:|      ..||:...:..|.. :||:           ||...|.|| .:::.
  Rat   374 ETDQPTSPEDGRVSAPYITEECLRKLDTKQQTNTLLNLV-----------WRDSASEEVFTRMAS 427

  Fly   473 ICGMYYAALNTLSQM------KLDILTGICYSDNVLYDIWLLITSLGPNC---GMKEYLELLKSE 528
            ||       :||...      |:.:|..:.::...|..:|.||:|:....   .|...|:::...
  Rat   428 IC-------HTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMTTQMITGSMVPLLQVISRG 485

  Fly   529 TNLQKPQTAMLM----LFCDCMTHYVTILDEHEMYTE-----------QNPFKLNDYVLLTYFLN 578
            :.:....::.::    ||....:|.:..:.::|.:.:           ..||.|.:.:||:..|.
  Rat   486 SPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQLSMMPFTLEELILLSRCLR 550

  Fly   579 NI---LYKL--------INDNLLAGAKNI-------VQH----------PVFLSLHTLMLCLYRR 615
            :.   :.||        :.:..::..::|       :||          .:|..:..|:..|..|
  Rat   551 DACLGIIKLAYPETKPEVREEYVSAFQSIGVTTNSEMQHCIQMEQKRWVQLFKVITNLVKMLKSR 615

  Fly   616 DCRRPFTPPKHWL---------------IP------------EVKP--STFINDLEK-----AKR 646
            |.||.|.||.|||               :|            .:.|  ||....||.     ::.
  Rat   616 DTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLEVGLESPPLSVSEE 680

  Fly   647 NAMLLLAKMPHIIPHEDRVKLFRKFVQNEKAVM--------GLTESACASPRSALIVIHRDRIVE 703
            ..:.:|.::|.::|.|:|||:|::.:..:|..:        |:.           :.|.|:.|.|
  Rat   681 RQLAILTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGIN-----------VTIRRNYIYE 734

  Fly   704 DGYRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTTSDQR 768
            |.|.:|:.:....||..|||..:|..||.|||||..|:|:|||.|.:|..|:|:...||||::..
  Rat   735 DAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGL 799

  Fly   769 LYPSPIS--YVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCMDELPS 831
            |||:|.:  .|.|:....:.|:|||||||:||.::|::|||.||||:|||.:...   .:..|.|
  Rat   800 LYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADV---DIHHLAS 861

  Fly   832 LDNELYRSLTFIKHYKQDVSDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFF 896
            ||.|:|::|.|:|.|::||.:|.|.|:|..:.:|:...:.|..|||...|...|::.|||.:|.:
  Rat   862 LDPEVYKNLLFLKSYEEDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTGANRIAYIHLVADY 926

  Fly   897 HMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKDLQKHTHYYGGFHDTHQ 961
            .:|.|||...:||.:|..::|:.|||.:|...|:|.||||...|:.|:||:..|:|.||:...|.
  Rat   927 RLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPVSLEDLKSFTNYSGGYSADHP 991

  Fly   962 VVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIR 1026
            |:...|.:: :.||:||::..||||||||:||||||..|.|.|   |:.....:
  Rat   992 VIKIFWRVV-EGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAF---CIHNGGSD----------- 1041

  Fly  1027 GFFAIRKKDPLNRLPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFELS 1078
                      |.||||:|||.||||||.:..::.||.||.||:....|||||
  Rat  1042 ----------LERLPTASTCMNLLKLPEFYDEALLRSKLLYAIECAAGFELS 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	HECTc	694..1076	CDD:238033	159/383 (42%)
		HECTc	718..1075	CDD:214523	150/358 (42%)
Ube3c	XP_038964472.1	IQ	47..64	CDD:197470	6/16 (38%)
		HECTc	725..1081	CDD:238033	159/383 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1163565at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100865
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820