Protein Alignment CG5087 and Hectd2

DIOPT Version :10

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: XP_038936565.1
• Gene: Hectd2 / 309514
• RGDID: 1305536
• Length: 813
• Species: Rattus norvegicus
• Alignment Length: 902
• Identity: 201/902 - (22%)
• Similarity: 327/902 - (36%)
• Gaps: 253/902 - (28%)

  Fly   306 GTSMPGTKSLAFLGNIVNLFNID-----GQGESKELAYPLLTETTTSLLELIPNTVTT------- 358
            |:|:|||...|  ||..:....|     |||.      |:.:|        :|.:..|
  Rat    34 GSSLPGTGGPA--GNGRSRGRRDPEEFKGQGP------PVGSE--------VPGSSATTGEGKAR 82

  Fly   359 ------KGVFTQWHELLGWHTPGPEPAQNQ----NVAL---------------IKKQFHMLWDHR 398
                  ||..:.:...:...|...|.|:|:    ::||               ::::..|..|..
  Rat    83 GLDRGSKGQISTFSSFVSSVTQKKEAAENRSSPTHLALPNIRNVRDLPPICLDVRQKQRMSMDSL 147

  Fly   399 CIKLLLGDLLKQINLNYERIEFQSPQQPSISNLLRRALERSSTRG---------------VNLMG 448
            ..::.:..|.:.|          .|.||.........||::...|               ...:.
  Rat   148 SSEVKVPPLPEPI----------LPSQPKTVKDFEEDLEKAEATGNWKTVHAFYITAFDSFTELN 202

  Fly   449 VASSKQSKQQWRKLDSAEVVQVSRICGMYYAALNTLSQMKLDILTGICYSDNVLYDIWLLITSLG 513
            .|..|.:...:..::.:. :..:.:..::.|.|||...::..:|.||.   |.|...|     .|
  Rat   203 AAFKKDATASFNTIEDSG-INANLVNAVFDALLNTPQDIQKSVLKGII---NSLLQEW-----KG 258

  Fly   514 PNC--GMKEYLELLKSETNLQKPQ---TAMLMLFCDCMTHYVTILDEHEMYTEQNPFKLNDYVLL 573
            |..  .::.|..|      ||.||   |:..:::...:....|:::.             |:..|
  Rat   259 PRTKDDLRAYFIL------LQNPQFNITSTYVIYAHLLRQIATLVEA-------------DHHFL 304

  Fly   574 TYFLNNILYKLINDNLLAGAKNIVQHPV-FLSLHTLMLCLYRRDCRRPFTPPKH-------WLIP 630
            .::|..:..|..        |.:|:..: |:||...           |..|.:.       |.||
  Rat   305 VHWLKKLSQKKF--------KQLVERLLQFVSLRLF-----------PAKPEEFPPLTKCTWWIP 350

  Fly   631 EVKPSTFINDLEKAKRNAMLLLAK---MPHIIPHE-------DRVKLFRKF-------------- 671
            ..           ||..|:|..|.   .|.::|:.       |.:.|..::
  Rat   351 SA-----------AKVLALLNTANNLVHPPLVPYTDFYNSTLDHIDLMEEYHTWQSFGNSHSRFS 404

  Fly   672 ----------------VQNEK-------AVMGLTESACASPRSAL------IVIHRDRIVEDGYR 707
                            :|.:.       |...|.:......|..:      :.:.|..:|.|...
  Rat   405 FCQYPFVISITAKKIIIQRDSEQQMISIARQSLVDKVSRRQRPDMNMLFLNMKVRRTHLVSDSLD 469

  Fly   708 QLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTTSDQRLYPS 772
            :|..:... ||..::|.|:.     |||:|..|:.||:....|:::|.|...:|....|...:..
  Rat   470 ELTRKRAD-LKKKLKVTFVG-----EAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWF 528

  Fly   773 PISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLG--------QTQQALYS-CMDE 828
            . |:..||:.| |..||.::|.|||..|.:|:.|......:||.        .|...:.| .:|:
  Rat   529 S-SFKCDNYSE-FRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPVVPSDQSTPVGICSVTIDD 591

  Fly   829 LPSLDNELYRSLTFIKHYKQDV-SDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHY 892
            |..:..||...|..:..|:.:| .|...||.|.|:..|.|.:..|.|||....|.:.|:..|:..
  Rat   592 LCQIMPELAHGLKELLSYEGNVEEDFYSTFQVFQEEFGVIKSYNLKPGGDKIPVTNQNRREYVQL 656

  Fly   893 MAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSP-LDLKDLQKHTHYYGGF 956
            ...|.:|..|.:|..||..||.|:.....|.|..|.|::.|:.|  || ||:..||:.|. |.|:
  Rat   657 YTDFLLNKSIYKQFAAFYCGFHSVCASNALMLLRPEEVEILVCG--SPELDMHALQRSTQ-YDGY 718

  Fly   957 HDTHQVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTI 1021
            ..|...:.:.||::. .|..|.:|..|.|.|...:.|:.|.|.|.
  Rat   719 AKTDLTIRYFWDVVL-GFPLELQKKLLHFTTGSDRVPVGGMADLN-------------------- 762

  Fly  1022 GSVIRGFFAIRKKD-PLNRLPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFEL 1077
                   |.|.|.: ..|.||.:.||||.|.||.|:.|..|:.||...:|::.||.|
  Rat   763 -------FKISKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGL 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	IQCD	20..50	CDD:467745
		HECTc	694..1076	CDD:238033	116/393 (30%)
Hectd2	XP_038936565.1	HECTc	454..811	CDD:238033	116/395 (29%)