DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5087 and Bag3

DIOPT Version :9

Sequence 1:NP_648279.1 Gene:CG5087 / 39035 FlyBaseID:FBgn0035953 Length:1078 Species:Drosophila melanogaster
Sequence 2:NP_001011936.1 Gene:Bag3 / 293524 RGDID:1307794 Length:574 Species:Rattus norvegicus


Alignment Length:482 Identity:94/482 - (19%)
Similarity:160/482 - (33%) Gaps:170/482 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   371 WHTP-----GPE--------PAQNQNVALIKKQFHMLWDHRCIKLLLGDLLKQINLNYERIEFQS 422
            |:.|     ||:        |:::.:..|..::.|.::.    :|..|.:  .|.:::|..|.:.
  Rat    51 WNDPRVPPEGPKETASSANGPSRDGSRLLPAREGHPIYP----QLRPGYI--PIPVHHEGSENRQ 109

  Fly   423 P------QQPSISNLLRRAL------ERSSTRGVNLMGVASSKQSKQQWRKLDSAEVVQVSRICG 475
            |      .||.:......|.      .:|..||    ||..:.|:.:|..::.:|...|.....|
  Rat   110 PHLFHAYSQPGVQRFRTEAAAAAPQRSQSPLRG----GVTETTQTDKQCGQVPAAATAQPPTAHG 170

  Fly   476 MYYAALNTLSQMKLDILTGICYSDNVLYDIWLLITSLGPNCGMKEYLEL-LKSETNLQKPQTAML 539
            ...:.....|.......:....|..        .:|||.:...:.|:.: :..|.|:.:| .|..
  Rat   171 PERSQSPAASDCSSSSSSASLPSSG--------RSSLGSHQLPRGYIPIPVIHEQNITRP-AAQP 226

  Fly   540 MLFCDCMTHYVTILDEHEMYTEQNPFKLNDYVLLTYFLNNILYKLINDNL--------------L 590
            .......|||.....|   |..|.|               :.:|:..|:.              :
  Rat   227 SFHQAQKTHYPAQQGE---YQPQQP---------------VYHKIQGDDWEPRPLRATSPFRSPV 273

  Fly   591 AGAKN----------IVQHPVFLSLHTLMLCLYRRDCRRPFT----PP------KHWLIPEVKPS 635
            .||.:          .|..|..:.:||::      |..:|.|    ||      |    ||.||.
  Rat   274 RGASSREGSPARSGTPVHCPSPIRVHTVV------DRPQPMTHREPPPVTQPENK----PESKPG 328

  Fly   636 TFINDLEKAKRNAMLLLAKMPHIIPHEDRVKLFRKFVQN-----------EKAVMGLTES--ACA 687
            ....||.             |..||    :::.|:...:           ||..:.::.:  .|.
  Rat   329 LAGPDLP-------------PGHIP----IQVIRREADSKPVSQKPPPPAEKVEVKVSSAPIPCP 376

  Fly   688 SPRSALIVIHRDRIVEDGYRQLAAQPTQA----------LK-----------GVIRVRFINQ--Q 729
            ||..|      ...|....:.:||:|..|          ||           ||::|..|.:  |
  Rat   377 SPGPA------PSAVPSSPKNVAAEPKAAPSPAPAEAASLKSGDAEAPHKHPGVLKVEAILEKVQ 435

  Fly   730 GLHEAGIDQDG--VFKEFL--EETIKK 752
            ||.:|..:.:|  ..|::|  ||.:.|
  Rat   436 GLEQAVDNFEGKKTDKKYLMIEEYLTK 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5087NP_648279.1 HECTc 694..1076 CDD:238033 21/86 (24%)
HECTc 718..1075 CDD:214523 15/52 (29%)
Bag3NP_001011936.1 WW 23..55 CDD:197736 1/3 (33%)
BAG 423..500 CDD:214591 14/40 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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