DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5087 and Yap1

DIOPT Version :9

Sequence 1:	NP_648279.1	Gene:	CG5087 / 39035	FlyBaseID:	FBgn0035953	Length:	1078	Species:	Drosophila melanogaster
Sequence 2:	XP_006509915.1	Gene:	Yap1 / 22601	MGIID:	103262	Length:	494	Species:	Mus musculus

Alignment Length:	222	Identity:	47/222 - (21%)
Similarity:	83/222 - (37%)	Gaps:	64/222 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 QFEKLQPAMQKICCNIQGHLVQHDFYKIMRLVLIRGTVREELSVKPVTLVA--IITLCLRPLI-- 246
            |.::||...:::      .|.|.:.::.:|...||       ::.|.|..|  ...|.||..:
Mouse   294 QLQQLQMEKERL------RLKQQELFRQVRPQAIR-------NINPSTANAPKCQELALRSQLPT 345

  Fly   247 ---DGNFSRNLLAKFLSEIL-------SVPAL---IYHLQQ------------SVPQCLEQF-SS 285
               ||.....:.:..:|:.|       |.|.|   .||.:.            |:|:..:.| :|
Mouse   346 LEQDGGTPNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSIPRTPDDFLNS 410

  Fly   286 MGLLKKALSIS-----GDVQWFEEFGTSMPGTKSLAFLGNIVNLFNIDGQG---ESKELAYPLLT 342
            :..:....:||     .....|.::..::|||.        |:|..::|..   |.:|| .|.|.
Mouse   411 VDEMDTGDTISQSTLPSQQSRFPDYLEALPGTN--------VDLGTLEGDAMNIEGEEL-MPSLQ 466

  Fly   343 ETTTSLL----ELIPNTVTTKGVFTQW 365
            |..:|.:    .::..|...|..|..|
Mouse   467 EALSSEILDVESVLAATKLDKESFLTW 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG5087	NP_648279.1	HECTc	694..1076	CDD:238033
CG5087	NP_648279.1	HECTc	718..1075	CDD:214523
Yap1	XP_006509915.1	FAM181	<61..>141	CDD:373671
		WW	159..188	CDD:238122
		WW	217..246	CDD:366073
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900