Protein Alignment CG5087 and etc-1

DIOPT Version :9

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: NP_495842.1
• Gene: etc-1 / 174388
• WormBaseID: WBGene00008429
• Length: 1001
• Species: Caenorhabditis elegans
• Alignment Length: 1204
• Identity: 264/1204 - (21%)
• Similarity: 479/1204 - (39%)
• Gaps: 338/1204 - (28%)

  Fly     5 NQKASFLEQTKAAREERALEKRREQAAILLQSTLKGYAARRKYQKRIIL--DFDAMFTENHDDKD 67
            |::.:||.:.:....:|..::::|:||..:|...:|:  |.::.:|::.  :|||:     .|:.
 Worm     6 NERDNFLNRLREMEHKREKDEKQEKAARKVQKFWRGH--RVQHNQRLLFRAEFDAV-----SDRQ 63

  Fly    68 AELELVASNVYPVLRRYLTQIRLDKSDVRARERLERICRYIIKAMESENTKLSYAALCLFKERSL 132
            ..||........::..|.|.        :..|||......::|...|:..         |::|
 Worm    64 RGLEETIKMAQLLVNFYETN--------KDEERLVMTLSELVKLKTSDKE---------FEKR-- 109

  Fly   133 PWIAHI-KILLTNCLTLLPELKPENHADSLSLALFLHTLVVFTAPKSWAILRNAQFEKLQPAMQK 196
              |... ::||..|.....:...||       .:|.|   :|...:.:....:..||    |..|
 Worm   110 --IRETQRLLLARCCIKFLKNATEN-------TIFFH---IFRYLEDYVTCHSKLFE----ASSK 158

  Fly   197 I-CCNIQGHLVQHDFYKIMRLVLI---RGTVREELSVKPVTLVAII------------------- 238
            : ..|.:.||::         .||   .|...|..|:.|..|..:.
 Worm   159 LGLFNAEFHLLE---------ALIGKPTGKTVERASLNPRILQLLTRIFETFVNPSRSTSVSVNV 214

  Fly   239 ------TLCLRPLIDGNFSRNLLAKFLSEILSVPALIYHLQQSVPQCLEQFSSMGLLKKALSISG 297
                  |:|:. :.|.||| |.:..::.:         |::.:.|.....|.:|
 Worm   215 ANRLLKTICVN-ITDLNFS-NYILYYIKD---------HIKPTSPNFTNLFEAM----------- 257

  Fly   298 DVQWFEEFGTSMPGTKSLAFLGNIVNLFNIDGQGESKELAYPLLTETTTSLLELIPNTVTTKGVF 362
                           ||:    :|:|.:.:  :.|..|.|...|.....|.:..:.||
 Worm   258 ---------------KSV----DILNNWKV--RPEIAETASLRLQSIFVSQIVHVSNT------- 294

  Fly   363 TQWHELLGWHTPGPEPAQNQNVALIKKQFHML---WDHRCIKLLLGDLLKQINLNYERIEFQSPQ 424
                             |:::|   |:.|:.|   .:|.      ..:::.:|:..:..|| ...
 Worm   295 -----------------QSEDV---KQYFNSLAVFLEHH------SKIMRSLNVKEDLSEF-GRL 332

  Fly   425 QPSISNLLRRALE---------RSSTRGVNLMGVASSKQSKQQWRKLDSAEVVQVSRICGM--YY 478
            :.|::|.|::..|         |::....||.|                   |||..|..:  |:
 Worm   333 RTSVNNHLKQYCEEMLISNEFRRAACIYANLPG-------------------VQVETIISLRKYF 378

  Fly   479 AALNTLSQMKLDILTGICYSDNVLYDIWLLITSLGPNCGMKEYLELLKSETNLQKPQTAMLMLFC 543
            :..       ||:|..   |:..:..::..|..|.||   .|:     ...:.:.|:...|.|||
 Worm   379 SQF-------LDLLAA---SNTFVEALYAFIARLCPN---GEF-----DPIDAKSPKVNALELFC 425

  Fly   544 DCMTHYVTILDEHEMYTEQNPFKLNDYVLLTYFLNNILYKLIN--------DNLLAGA------- 593
            :|:...|:.:.:.: :...:.|.  |:.....||.::..|||:        .:|.:|.
 Worm   426 NCLNKRVSSVADSD-FVPTDIFV--DFDHTVEFLRDVSIKLIHLMFPTMARGDLYSGNLKEKMYK 487

  Fly   594 -----KNIVQHPVFLSLHTLMLCLYRRDCRRPFTPPKHWL------------------------- 628
                 |::.:     |:.:::..:|::|.|..:.|.:.|.
 Worm   488 AETDWKDVTE-----SVFSILGAIYQKDIRLKYFPEEFWTNHGREVLSGIGEHRRMPRRRMPNGR 547

  Fly   629 --IPEVKPSTFI---------------------NDLEKAKRNAMLLLAKMPHIIPHEDRVKLFRK 670
              |.....:.|:                     |:|....|.|:.::..:|.|:|..||||||.:
 Worm   548 LQIERTMDTEFVERLAAIYEMDSDSENDDEDEDNNLPAVLRRAICVMKHIPFIVPFMDRVKLFTR 612

  Fly   671 FVQNEKAV-------MGLTESACASPRSALIVIHRDRIVEDGYRQLA----AQPTQALKGVIRVR 724
            .:..:|..       ||....:        :.:.||::..|.:...|    ......||.::||:
 Worm   613 LLNQDKEKHYTSTFGMGFNGPS--------VTVRRDQVYMDAFETFAPKMQGDKVNDLKSMVRVK 669

  Fly   725 FINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTTSDQRLYPSPIS--YVQDNHLELFEF 787
            .:|..|::|:|||..|:|:|||.|.:|..|:.....|..|..:.|||:|.:  .:..:.|..|:|
 Worm   670 MVNWAGMNESGIDGGGIFREFLSELLKTAFNVERGFFTFTESKLLYPNPTAPFLLGVDCLAHFQF 734

  Fly   788 VGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCMDELPSLDNELYRSLTFI-KHYKQDVS 851
            :|||:||.:||..:.:|.||.||::|:. :|.:.....:..:.|.|..:::.|..: |...:::.
 Worm   735 IGRMIGKLIYERQLQEVRFAEFFIAQIF-ETDKNKDVDLQHMKSFDPIIFKHLKALQKMNNRELD 798

  Fly   852 DLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSI 916
            :|.|.|||....||.:..:.|.|.|....|...|...|:.....:|:..:|.....|..:|...|
 Worm   799 ELQLDFSVVTSDMGLVRNVNLKPNGSKFRVTVENVHEYVRLYVNYHLKQRIASMVDAVRKGISEI 863

  Fly   917 VNPEWLSLFSPPELQRLISGDTSPLDLKDLQK--HTHYYGGFHDTHQVVCWLWDILAKDFTEEER 979
            ::.||:.:|:|.|||.:|:|.......|:|:|  ...:..|..|.:....: ||::.| .:.:::
 Worm   864 ISIEWMRMFAPHELQIMIAGYEEVFTAKELRKFCELRFAAGTQDINYEEMF-WDVIDK-LSNDDK 926

  Fly   980 KLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSS 1044
            |..|||||.||:.|:.||..::|...:..:..||||                        ||||:
 Worm   927 KALLKFVTGCSRAPVDGFKSIQPRMGVLVIPSSDDE------------------------LPTSA 967

  Fly  1045 TCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFELS 1078
            ||.|:|::|.|..::.|.:|||||::|..||||:
 Worm   968 TCMNMLRIPKYSNRTKLEEKLRYAINSGAGFELA 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	HECTc	694..1076	CDD:238033	118/390 (30%)
		HECTc	718..1075	CDD:214523	112/361 (31%)
etc-1	NP_495842.1	HECTc	661..998	CDD:214523	113/363 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1163565at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100865
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1831
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750