Protein Alignment CG5087 and nedd4

DIOPT Version :10

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: XP_031755033.1
• Gene: nedd4 / 100496333
• XenbaseID: XB-GENE-478443
• Length: 1283
• Species: Xenopus tropicalis
• Alignment Length: 427
• Identity: 128/427 - (29%)
• Similarity: 211/427 - (49%)
• Gaps: 50/427 - (11%)

  Fly   655 MPHIIPHEDRVKLFRKFVQNEKAVMGLTESACASPRSALIVIHRDRIVEDGYRQ-LAAQPTQALK 718
            :|:...::.:.:.|||.::.:..:          |....:.:.|..|:||.||: :|.:..:.||
 Frog   899 VPYSRDYKRKYEYFRKKLKKQIDI----------PNRFEMKLRRTAILEDSYRRIIAVKRPEFLK 953

  Fly   719 GVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFK--TTSDQRLYPSPIS-YVQDN 780
            ..:.:.|.|::||     |..||.:|:.....|::|:|...||:  .|.:..|..:|.| ...::
 Frog   954 ARLWIEFDNEKGL-----DYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNED 1013

  Fly   781 HLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCMDELPSLDNELYRSLTFIKH 845
            ||..|:|:||:.|.|||.|.::|..|...|...:| |....||    ::.|:|:|.|.||.:|
 Frog  1014 HLSYFKFIGRVAGMAVYHGKLLDAFFIRPFYKMML-QKPIILY----DMESVDSEYYNSLQWI-- 1071

  Fly   846 YKQDVSDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFN 910
            .:.|.|.|:|.|:||:::.|:.....|..||...:|.:.||..|||.:..:....::::|..||.
 Frog  1072 LENDPSGLDLCFTVDEELFGQTHQHELKAGGSQILVTNKNKKEYIHLVIQWRFMNRVQKQMAAFK 1136

  Fly   911 RGFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKDLQKHTHYYGGFHDTHQVVCWLWD-ILAKDF 974
            .||..::..:.:.:|...||:.|:.| ...:|:.:.::||.|..|:...|||:.|.|. :|..|
 Frog  1137 EGFFELIPQDLIKIFDENELELLMCG-LGDVDVNNWREHTKYKNGYSQGHQVIQWFWKAVLMMD- 1199

  Fly   975 TEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNR 1039
             .|:|...|:|||..|:.|:.|||.|                    .||.....|.:.|.....:
 Frog  1200 -AEKRIRLLQFVTGTSRVPMNGFAEL--------------------YGSNGPQLFTVEKWGTPEK 1243

  Fly  1040 LPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFE 1076
            ||.:.||||.|.||.|:....|.|||..|:.:..||:
 Frog  1244 LPRAHTCFNRLDLPPYESFEDLWDKLHIAIENAQGFD 1280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	IQCD	20..50	CDD:467745
		HECTc	694..1076	CDD:238033	122/386 (32%)
nedd4	XP_031755033.1	C2	<485..538	CDD:472691
		WW	579..611	CDD:197736
		WW	735..764	CDD:459800
		WW	807..836	CDD:459800
		WW	857..889	CDD:197736
		HECTc	950..1279	CDD:214523	114/363 (31%)