Protein Alignment CG5087 and hectd2

DIOPT Version :10

• Sequence 1: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: NP_001106408.1
• Gene: hectd2 / 100127570
• XenbaseID: XB-GENE-958149
• Length: 753
• Species: Xenopus tropicalis
• Alignment Length: 762
• Identity: 180/762 - (23%)
• Similarity: 284/762 - (37%)
• Gaps: 216/762 - (28%)

  Fly   423 PQQPSISNLLRR---ALERSSTRGVNLMGVASSKQSKQQWRKL--------DS------------ 464
            ||.|:.:..|:.   .||::.:.|              :||.:        ||
 Frog   100 PQIPTRNKTLKDFQVDLEKAKSTG--------------EWRTIHDFYLTTFDSFLELNAAFKRDV 150

  Fly   465 ---AEVVQVSRI-----CGMYYAALNTLSQMKLDILTGICYSDNVLYDIWLLITSLGPNC--GMK 519
               ...::.|||     ..:|...|.|...::..:|.||.   |.|...|     .||..  .::
 Frog   151 SSFVNTIEDSRINTKFLNAVYDTLLTTSQDIQKTVLKGII---NSLLREW-----KGPRTKDDIR 207

  Fly   520 EYLELLKSETNLQKPQTAMLMLFCDCMTHYVTILDEHEMYTEQNPFKLNDYVLLTYF--LNNILY 582
            .|..|.:   |.|...|:..:::...:....|:.|            .:::.|:.:|  ::...:
 Frog   208 AYFILTQ---NPQFSSTSTYVIYAHLLRQIATLSD------------TDNHFLIHWFKKMSQKRF 257

  Fly   583 KLINDNLLAGAKNIVQHPVFLSLHTLMLCLYRRDCRRPFTPPKH-------WLIPEVKPSTFIND 640
            |.:.|.||.          |:||...           |..|.:.       |.||......
 Frog   258 KQLVDRLLQ----------FISLRLF-----------PAKPEEFPPLAKCTWWIPSATKVL---- 297

  Fly   641 LEKAKRNAMLLLAKMPHIIPHE-------DRVKLFRKF--------------------------- 671
               |..||...|:. |.:||:.       |.:.|..::
 Frog   298 ---ALLNAANTLSN-PPLIPYTDFYNSTLDHIDLMEEYQTWQFYGNSHRFSFCQFPFIISIAAKK 358

  Fly   672 --VQ--NEKAVMGLTESACASPRSAL-----------IVIHRDRIVEDGYRQLAAQPTQALKGVI 721
              :|  :|:.::.:...:.....|..           |.:.|.::|.|...:|..:... ||..:
 Frog   359 VIIQKDSEQQMISIARQSLVDKVSRRQKPDMNMLFLNIKVRRLQLVSDSLDELTRKRAD-LKKKL 422

  Fly   722 RVRFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTTSDQRLYPSPISYVQDNHLELFE 786
            :|.|:.     |||:|..|:.||:....|:::|.|...:|....|...:... |:..||:.| |.
 Frog   423 KVTFMG-----EAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSNCHWFS-SFKCDNYSE-FR 480

  Fly   787 FVGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCMDELP------SLDNELYRSLTFIKH 845
            .||.::|.|||..|.:|:.|......:||   ...:..|...:|      :|| :||:.:..:.|
 Frog   481 LVGTLMGLAVYNSITLDIRFPPCCYKKLL---SPPIVPCDQNMPVGIAPVTLD-DLYQIMPELAH 541

  Fly   846 -------YKQDV-SDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQI 902
                   |..:| .|...||.|.|:..|.|.:..|.|||....|.:.|:..|:.....|.:|..|
 Frog   542 GLNELLCYDGNVEEDFYSTFQVFQEEFGTIKSYNLKPGGDKIPVTNQNRKEYVQLYVDFLLNKSI 606

  Fly   903 REQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSP-LDLKDLQKHTHYYGGFHDTHQVVCWL 966
            .:|..||..||.|:.....|.|..|.|::.|:.|  || ||:..||:.|. |.|:..|...|.:.
 Frog   607 YKQFSAFYYGFHSVCASNALMLLRPEEVEILVCG--SPELDMHALQRSTQ-YDGYLKTDVTVRYF 668

  Fly   967 WDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAI 1031
            ||::. .|..|.:|..|.|.|...:.|:.|.|.|.                           |.|
 Frog   669 WDVVL-GFPLELQKKLLHFATGSDRVPVGGMADLN---------------------------FKI 705

  Fly  1032 RKKD-PLNRLPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFEL 1077
            .|.: |.|.||.:.||||.|.||.|:.|..|:.||..|:|:..||.|
 Frog   706 SKSETPSNWLPIAHTCFNQLCLPPYKTKKELKQKLTIAISNAEGFGL 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5087	NP_648279.1	IQCD	20..50	CDD:467745
		HECTc	694..1076	CDD:238033	120/397 (30%)
hectd2	NP_001106408.1	HECTc	394..751	CDD:238033	120/399 (30%)