Protein Alignment smg and samd4a

DIOPT Version :9

• Sequence 1: NP_001137924.1
• Gene: smg / 39034
• FlyBaseID: FBgn0016070
• Length: 1109
• Species: Drosophila melanogaster
• Sequence 2: XP_012824082.1
• Gene: samd4a / 780035
• XenbaseID: XB-GENE-978113
• Length: 719
• Species: Xenopus tropicalis
• Alignment Length: 1058
• Identity: 238/1058 - (22%)
• Similarity: 357/1058 - (33%)
• Gaps: 379/1058 - (35%)

  Fly    73 LFCEQVTTVTNLFEKWNDCERTVVMYALLKRLRYPSLKFLQYSIDSNLTQNLGTSQTNLSSVVID 137
            :|.:||..::..|:.||:||:||.:.:||||:.....:|||..::.:|     ...|.|.  :::
 Frog     2 MFRDQVGMLSGWFKGWNECEQTVALLSLLKRVSRTQARFLQICLEHSL-----VDCTELH--ILE 59

  Fly   138 INANNPVYLQNLLNAYKTFQPCDLLDAMSSSSSDKDSMPCYGSDFQITTSAQCDERKLYARKEDI 202
            ..||||.                :::.....|.||                             :
 Frog    60 GEANNPA----------------IINQWQQESKDK-----------------------------V 79

  Fly   203 LHEVLNMLPLLKPGNEEAKLIYLTLIPVAVKDTMQQIVPTELVQQIFSYLLIHPAITSEDRRSLN 267
            :.::|..||||||||.:||:.|:.|:|..:..:::.....|..:|:.||.|||||.:.:||.:|.
 Frog    80 ISQLLTHLPLLKPGNIDAKVAYMKLLPKILAHSIEHNQHIEESRQLLSYALIHPATSLDDRSALA 144

  Fly   268 IWLRHLEDHIQAAAAGLTNRSYFLQPSPQLVAGGSSTGSGSCSSSATSSSTASCSSVASSSLCPA 332
            :||.||||.                     .:|..||.| .|.|.:.............:|
 Frog   145 MWLNHLEDR---------------------TSGNFSTQS-RCRSDSLDYGQMQYYHQRQNS---- 183

  Fly   333 SGSRSSRTNDWQTIAPPSKQLQNKLAGDWRGNGGG---SSSG--SINPLCDNLNGITLNELASSQ 392
                ..:.|.|    |.|:.             .|   ||||  ..|..|:|.:
 Frog   184 ----DDKQNGW----PNSRD-------------SGICVSSSGWQEKNTGCENGH----------- 216

  Fly   393 NSLGLSLEGSSSLVNGVVAGAGSMLGIAGGDDHDTSFSKNGTEILDFDPVTADMGEACSLASSSL 457
                |.|..|||:.:.:.|...:...|..|..|.:...:                      |.||
 Frog   217 ----LPLYSSSSVPSTINAIGTNTSTILSGQTHHSPLKR----------------------SVSL 255

  Fly   458 CGRNGGNPVEDRSQPPPNLQQQLLQPPPYASILMGNVGDQFGEINRWSLDSKIAALKTRRSNSLT 522
                         .||.|:..|.|.                   :.|.....   |:.|.|..:.
 Frog   256 -------------TPPMNVPNQPLG-------------------HGWMSHED---LRARGSQGIP 285

  Fly   523 TQTISSCSSSSNSSVITVNDNCSNSTENLAQFANKPRSFSLSIEHQRGALMNSGSDTRLDEFKPN 587
            :   .....|..|||                                 |...||....|:|....
 Frog   286 S---DHAPLSPQSSV---------------------------------ASSGSGGSEHLEEQSTA 314

  Fly   588 YIKFHTRNVGMSGIGLWLKSLRLHKYIELFKNMTYEEMLLITEDFLQSVGVTKGASHKLALCIDK 652
            ...|.....||..:..||||||||||..||.:|:||||:.:.|..|::..|||||.||:.:.|.|
 Frog   315 RNTFQDEGSGMKDVPAWLKSLRLHKYAALFSHMSYEEMMSLNECQLEAQNVTKGARHKIVISIQK 379

  Fly   653 LKERANILNRVEQELLSGQMELSTAVEELTNIVLTPMKPLESPGPPEENIGLRFLKVIDIVTNTL 717
            ||||.|:|..:|:::|.|. .|...::||..::|||:|.. ||    :|            :||.
 Frog   380 LKERHNLLKTLERDILEGG-NLRVPLQELHQMILTPIKTY-SP----QN------------SNTE 426

  Fly   718 QQDPYAVQDDETLGVLMWILDRSIHNEAFMNHASQLKDLKFKLSKMKISMVPKMHHVKPAGVGPN 782
            :.:..| ....||.|.             .|.||:.||        ..|...:.||:.
 Frog   427 EHNREA-DSQPTLLVA-------------ENQASESKD--------SASAGIQQHHIS------- 462

  Fly   783 NGNINKPRWNGKTRKCDTKNGSNDRINNRKNSNDMLNFSLNCLPHPLPHHSQQAPPPLPQFDYNG 847
                          .|:|::|.                                 .|||:.|..|
 Frog   463 --------------NCETESGG---------------------------------VPLPEGDLPG 480

  Fly   848 YGGGPSHQPQYKSSSYPSFMGN--PQQQPPPPPSSKSHHHPQQMQQMLQQHNHFPALPQQTPPQS 910
                          .:...||.  .|.....|.......:.|.:.:.| .|..|      |..|.
 Frog   481 --------------QFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCL-THEAF------TETQK 524

  Fly   911 HRRSLNNLILVAGGPQQPQQLIFK--PGQGVLTNNGSNDNLVLERNQQSQQQQQQRKLS-----G 968
            .|        :....||.|:| |:  |.:.:|...|               .:||||.|     |
 Frog   525 KR--------LLSWKQQVQKL-FRSFPRKSLLDVAG---------------YRQQRKTSVDVLIG 565

  Fly   969 GVSSAEQQPKKTMAAV---VMVSNPNQNQ-DQHDQPQILINNNNNNSMLNNNLINQQQLQLLAAA 1029
            ..:..:.....|..:|   :...||.|.| ...:.|...::....:|:|.    ..|:......|
 Frog   566 SRAFGQSNSLPTAGSVGSGIARRNPRQFQIPSRNLPSTRLSLLGASSLLG----APQRASASNPA 626

  Fly  1030 AAAVGSGSCLCSNGGGGACVHNICHQSSKNNNHGVDHCLSQSPLGSLGMSPH----VTEYKMNDF 1090
            ....|..:...:|.||...:.:..|.|.:.......|...|:.|  :...|.    |||..:|:
 Frog   627 MLKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQTML--MFQQPDFQVPVTEPDINN- 688

  Fly  1091 KSLEQLETLCRQMTEQAM 1108
                :||:||..|||.|:
 Frog   689 ----RLESLCLSMTEHAL 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smg	NP_001137924.1	SAM_Smaug	597..655	CDD:188956	31/57 (54%)
		SAM	601..656	CDD:197735	30/54 (56%)
		PHAT	656..763	CDD:204178	27/106 (25%)
samd4a	XP_012824082.1	SAM_Smaug	320..382	CDD:188956	31/61 (51%)
		SAM	325..383	CDD:197735	31/57 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	71	1.000	Domainoid score	I9271
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3760
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D297836at33208
OrthoFinder	1	1.000	-	-		FOG0002446
OrthoInspector	1	1.000	-	-		otm48734
Panther	1	1.100	-	-	O	PTHR12515
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1666
SonicParanoid	1	1.000	-	-		X2618
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190