DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5068 and PPE1

DIOPT Version :10

Sequence 1:NP_648277.3 Gene:CG5068 / 39032 FlyBaseID:FBgn0035951 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_011942.1 Gene:PPE1 / 856474 SGDID:S000001117 Length:400 Species:Saccharomyces cerevisiae


Alignment Length:416 Identity:105/416 - (25%)
Similarity:168/416 - (40%) Gaps:112/416 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 GGRIGRADSF--KKSRIRDY--KPG---------------MWNEFFAEKEDVTV-DEQRTFRIYR 63
            |..:|...||  :.:|.|.|  |.|               .|::||..||.|:: |.......|.
Yeast    36 GDALGSLPSFNGQSNRNRKYTGKTGSTTDRISSKEKSSLPTWSDFFDNKELVSLPDRDLDVNTYY 100

  Fly    64 TKQPEKPG-----PVLLLLHGGGYSALTWAHFCSEVTSMI--HCQCLCIDMRGHGDSKVDDEDD- 120
            |.......     |:.:..||.|.|.|::|:...|:.:.:  .|.|...|.|||.::|....|. 
Yeast   101 TLPTSLLSNTTSIPIFIFHHGAGSSGLSFANLAKELNTKLEGRCGCFAFDARGHAETKFKKADAP 165

  Fly   121 --LSADTLAKDIGDLILKLYPEEVPQ-------LFVVGHSMGGAIAVHFAHMALVPNL----IGI 172
              ...|:..||...|:...:..::.|       :.::|||:||:|.. ||:..|...|    :||
Yeast   166 ICFDRDSFIKDFVSLLNYWFKSKISQEPLQKVSVILIGHSLGGSICT-FAYPKLSTELQKKILGI 229

  Fly   173 TVIDVVEGTAMEALASMQSFLRSRPKYFQSIPNAIEWCIRSGQVRNVDSAKVSMPGQIINCTTNK 237
            |::|:||..|:.||..::.||::.|..|:||.:|::|.::....|...||::::|          
Yeast   230 TMLDIVEEAAIMALNKVEHFLQNTPNVFESINDAVDWHVQHALSRLRSSAEIAIP---------- 284

  Fly   238 LATNDLPLPDDVLEEAHHNSMFPNPFSISEDEESSPPGDDAADGSSESAAAGADFKKPNTTKSTT 302
                                                             |..|..|.....:.| 
Yeast   285 -------------------------------------------------ALFAPLKSGKVVRIT- 299

  Fly   303 EAAKNYTWRIDLSKSEKYWVGWFSGLSDKFLNLRLPKQLLLASIDGLDRTLTVGQMQGRFQMQVL 367
                      :|.....:|..||:.||..|:.|.:.|.|:||..:.||:.|.||||||::|:.|.
Yeast   300 ----------NLKTFSPFWDTWFTDLSHSFVGLPVSKLLILAGNENLDKELIVGQMQGKYQLVVF 354

  Fly   368 ARCGHAVHEDRPHEVAEVISGYLIRN 393
            ...||.:.||.|.:.|..:..:..||
Yeast   355 QDSGHFIQEDSPIKTAITLIDFWKRN 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5068NP_648277.3 MenH 46..262 CDD:440361 58/237 (24%)
PPE1NP_011942.1 Abhydrolase_1 114..366 CDD:395444 83/322 (26%)

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