Protein Alignment Galk and GALK2

DIOPT Version :10

• Sequence 1: NP_648276.1
• Gene: Galk / 39031
• FlyBaseID: FBgn0263199
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: XP_047288303.1
• Gene: GALK2 / 2585
• HGNCID: 4119
• Length: 477
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 201/488 - (41%)
• Similarity: 274/488 - (56%)
• Gaps: 61/488 - (12%)

  Fly    41 FKQQFGANPDFIVRVPGRVNIIGEHVDYCGYSVLPMAVSQSIFLAVAKNPSDS-QLQLRNLEEAK 104
            |..:||:.|.|.||.||||||||||:||||||||||||.|.:.:||  .|..: .|||.|....
Human     2 FNSKFGSIPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAV--EPVKTYALQLANTNPL- 63

  Fly   105 FTGYDADLKTLRIELPKSGGPAWYNYFLCGIKGIQESLGSQWKPIGMRIAVDGNVPLAAGLSSSS 169
            :..:......::|:..|   |.|:||||||:|||||..|.. ...||...||||:|.::||||||
Human    64 YPDFSTSANNIQIDKTK---PLWHNYFLCGLKGIQEHFGLS-NLTGMNCLVDGNIPPSSGLSSSS 124

  Fly   170 AMVSSAVLATAHVQGKKLDRRELASISAMCEQYIGTHSGGMDQAIAYLGRVGCAHHIEFHPKLKG 234
            |:|..|.|.|..|.|:.|.:.|||.|.|..|:||||..|||||:|::|...|.|..|||.| |:.
Human   125 ALVCCAGLVTLTVLGRNLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP-LRA 188

  Fly   235 TPVTLPAGKCFVVANSLAQKNKAASSDYNERVVECRLATRWLAKRKGLINWEDIVRFIDLEEACQ 299
            |.|.||:|..||:|||..:.||||:|.:|.||:|||||.:.|||.|.| .|:.::|..:::....
Human   189 TDVKLPSGAVFVIANSCVEMNKAATSHFNIRVMECRLAAKLLAKYKSL-QWDKVLRLEEVQAKLG 252

  Fly   300 MDNETFEKLIKDNLTKSNYTRADICKELGVTEQELETKFLSANTR-----HMEQ----------- 348
            :..|....:.:|.|....|...:||:.||::.:||.|:.||.||:     |:.|
Human   253 ISLEEMLLVTEDALHPEPYNPEEICRCLGISLEELRTQILSPNTQDGIILHIPQCCDENFMRFKQ 317

  Fly   349 -----------------------FKLRQRALHVIQESGRVAKFRKICEELAGGANKEGAKQLGEL 390
                                   |||.|||.||..|:.||.:|:|||||    |.:...:.||||
Human   318 FSHFSLSNSWDYMHPPSSCPVLIFKLYQRAKHVYSEAARVLQFKKICEE----APENMVQLLGEL 378

  Fly   391 MRQSHESLRELYECSHPDVERLIAISNQQNV-SARVTGAGWGGCIVAMCDSIEAADEYIKVLKRD 454
            |.|||.|.|::||||.|::::|:.|..:... .:|:||||||||.|:|..: :....::..:.:.
Human   379 MNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVPA-DKLPSFLANVHKA 442

  Fly   455 YYAQLPTHLLERHQPNNFSEVVFATLPGNGAEL 487
            ||.:....|....|.      :|||.||...|:
Human   443 YYQRSDGSLAPEKQS------LFATKPGGALEI 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galk	NP_648276.1	PLN02521	32..485	CDD:215285	200/484 (41%)
GALK2	XP_047288303.1	PLN02521	2..466	CDD:215285	200/483 (41%)