DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5644 and CHKov2

DIOPT Version :9

Sequence 1:	NP_648274.1	Gene:	CG5644 / 39029	FlyBaseID:	FBgn0035948	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_651387.1	Gene:	CHKov2 / 43068	FlyBaseID:	FBgn0039328	Length:	409	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	117/460 - (25%)
Similarity:	180/460 - (39%)	Gaps:	108/460 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RQLFS----QSKLVSFSIAHIACSAGSSSGDNYMSVVKRVTISQAGKDQDPELAGSEIVTVIVKR 100
            ::|||    ||.....:|.....::..|.|:||:::|.|:.|....||.     ..|.|:.|:|.
  Fly    12 KELFSSLLEQSNRNFKAIIKFVPTSAISKGENYLTIVLRIQIEMQLKDN-----SIEDVSYILKI 71

  Fly   101 QIASLSRRQLYRCEEAFSNEINAYRHLAP----LLAAHSR--------HQLFPVCHIAESQDRRD 153
            .:.....:..:  .|.|..|::.|.||.|    |.|.::.        |..||
  Fly    72 PLVPEDEKNDF--HEMFDAELDMYDHLIPELEDLYAKNTSISPKFKPVHLKFP------------ 122

  Fly   154 AEGGEPI----IVLQDLKAMGFRMKDRLAGLELSDCLLVMKKLAQLHAAS------LAAQELESS 208
               |||:    |:|:||:..|:|..||..|||..:...|:|||||.||||      |...|.:..
  Fly   123 ---GEPVKSDYILLEDLRKKGYRNADRTQGLEQFEVEAVLKKLAQWHAASAKRVVELGEYEKDIR 184

  Fly   209 SFAFHADHLQEIVYCDEAT-DFYATILDTSVQQALE------------SLGDANADDCLTTPIRL 260
            ...|..:| |:::  ||.. :|....|:...|..||            .|.|.|.:.....|:.|
  Fly   185 ESYFTTEH-QKLL--DEFNINFCMPFLECMQQYNLEPGQLVLISDYTSQLTDLNIEFGKNDPLEL 246

  Fly   261 LEELRTNLFENLKHEINATAAAPNSVICHGDLWVNNIMFR----SEPEEVIFFDLQAMRKSSPIF 321
                                    ||:.|||.|.||.||:    ||.|:|.|.|.|..:..:|..
  Fly   247 ------------------------SVLNHGDFWCNNFMFKYKNASEVEDVCFVDFQLPKYGTPAQ 287

  Fly   322 DILHFIYTSTRRPLRDVHTDTLLAAYSQALSEELRHQLEDTTAAERLEELCEAFSLQRLSSDYVR 386
            |:|..:.||.:..::....|..:..|.|.|.|.|          ..|.....|.:|.:..:...|
  Fly   288 DLLCILMTSPKFSIKLDKFDYFIEYYHQQLVEHL----------TMLNYNRNAPTLSKFHAHLHR 342

  Fly   387 QVHYGLAIGMWILPAVTFDP---NNLPNLDVMSEQNLTGKEIKCTQMLTSEYHMRIRELVMEFYE 448
            ...:.......:||.|...|   :::.|:...||:.:.   .|....|...|..:|:.::.....
  Fly   343 YSLWAFICAQRMLPIVLLPPDVDSHIGNVMGNSEEAIA---FKRKMFLLPAYVDQIKVILPWLIN 404

  Fly   449 LGYLQ 453
            .||::
  Fly   405 RGYIR 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5644	NP_648274.1	EcKinase	65..357	CDD:281023	93/330 (28%)
CG5644	NP_648274.1	P-loop_NTPase	<357..435	CDD:304359	13/80 (16%)
CHKov2	NP_651387.1	EcKinase	40..326	CDD:281023	94/344 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010