DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5644 and CG11892

DIOPT Version :9

Sequence 1:	NP_648274.1	Gene:	CG5644 / 39029	FlyBaseID:	FBgn0035948	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_651372.1	Gene:	CG11892 / 43053	FlyBaseID:	FBgn0039313	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	104/478 - (21%)
Similarity:	179/478 - (37%)	Gaps:	78/478 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ALAAAPTAGPSHGGLALTVSSAGGYDGTNQYEENAEHLRQLFSQSKLVSF------SIAHIACSA 60
            ||.|.|         .|||..:...:.|:.:.:..|.|.:.:.|..|..:      .|..:..:.
  Fly     9 ALDAIP---------KLTVPESLVPEETSVFLDAPEWLTESYLQDALRKYYKDQLIRINWVKVNP 64

  Fly    61 GSSSGDNYMSVVKRVTISQAGKDQDPELAGSEIVTVIVKRQIASLSRRQLYRCEEAFSNEINAYR 125
            ....|:||..|:.||.......|...:|....:.:.....:.|..:.:..    :.|:.|:..|.
  Fly    65 ALGKGENYGGVLTRVKAQFTRSDGSSQLGHYIVKSTFEGNEFAQNAMKPY----DIFNREMIIYE 125

  Fly   126 HLAPLLAAHSR-----HQLFPVCHIAESQDRRDAEGGEPIIVLQDLKAMGFRMKDRLAGLELSDC 185
            .:.|...|..|     .|:|     ||:.   ..:.....::.:||.|.||.|.|||.||:....
  Fly   126 QVLPKQKALLREIGDAEQIF-----AETM---AVDIDNSALIFEDLNARGFVMPDRLVGLDQKLA 182

  Fly   186 LLVMKKLAQLHAASLAAQELESSSFAFHADHLQEIV-------YCDEATDFYATILDTSVQQALE 243
            .:|::|||::||.|....|.|        :|:.|..       |.|.....:..:|..:.::..:
  Fly   183 RIVLRKLAKMHATSAVLNERE--------NHILESYDRGFFNRYTDNYEPAFVGMLQAATRRVAQ 239

  Fly   244 SLGDANADDCLTTPIRLLEELRTNLFENLKHEINATAAAPNSVICHGDLWVNNIMFR-----SEP 303
            ..|.....:.|...:.:..||...:|:.....||        |:.|||||.||::.:     .||
  Fly   240 WPGYEKYAEKLKALVPIYMELGKRIFDISPGHIN--------VLAHGDLWTNNVLVKYDKQTGEP 296

  Fly   304 EEVIFFDLQAMRKSSPIFDILHFIYTSTRRPLRDVHTDTLLAAYSQALSEELRHQLEDTTAAERL 368
            .:|:..|.|.....||..|:.:|:.:|....|...|.:.|:|.|.:..::.|:          :|
  Fly   297 IDVVIIDFQYTAWGSPALDLFYFMNSSLEFDLHQNHQEQLIAYYFRHFADTLK----------KL 351

  Fly   369 EELCEAFSLQRLSSDYVRQVHYGLAIGMWILPAVTFDPNNLPNLD----VMSEQNLTGKEIKCTQ 429
            :......||.:......::..|.....:.:.|.    ..|:...|    .:.|.|......|...
  Fly   352 QYRSTIPSLHQFHQQLQQKKFYAAHTSISVFPV----QRNVETADADFNALMENNQRAMNFKDAC 412

  Fly   430 MLTSEYHMRIRELVMEFYELGYL 452
            .........:|||:.:|...|.|
  Fly   413 YRNPIAQRILRELLPDFEAEGLL 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5644	NP_648274.1	EcKinase	65..357	CDD:281023	75/308 (24%)
CG5644	NP_648274.1	P-loop_NTPase	<357..435	CDD:304359	10/81 (12%)
CG11892	NP_651372.1	EcKinase	68..353	CDD:281023	76/322 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	4	3.910