DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5644 and CG31102

DIOPT Version :9

Sequence 1:	NP_648274.1	Gene:	CG5644 / 39029	FlyBaseID:	FBgn0035948	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001262951.1	Gene:	CG31102 / 326118	FlyBaseID:	FBgn0051102	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	512	Identity:	96/512 - (18%)
Similarity:	172/512 - (33%)	Gaps:	186/512 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DGTNQYEE----------NAEHLRQLFSQSKLVSFSIAHIACSAGSSSGDNYMSVVKRVTISQAG 81
            |.:|::..          |..:.::|..:.......|.:::....:..|:.|.|::.|:.|....
  Fly     3 DNSNKFSASSDVRIPAWINEAYFKRLLKREFREFRRILNLSIIPATPPGETYTSLLMRIVIDIEL 67

  Fly    82 KDQDPELAGSEIVTVIVKRQIASLSRRQLYRCEEA-----FSNEIN-------AYRHLAPLLAAH 134
            ||     ..|:..:.|||..:           ::|     |.|.:|       .|..:.|.|
  Fly    68 KD-----GFSQQKSYIVKTML-----------DDAQGNGGFVNTLNIFPKEKMMYETIIPNL--- 113

  Fly   135 SRHQLF----------PVCHIAESQDRRDAEGGEPIIVLQDLKAMGFRMKDRLAGLELSDCLLVM 189
              .||:          |.||.||     |.: |...:|.:||:...:|..:||.|.:::....|:
  Fly   114 --EQLYEEAGLSVKFAPKCHHAE-----DIK-GRICLVQEDLQTKKYRNINRLKGFDMAHMHRVL 170

  Fly   190 KKLAQLHAAS------------------LAAQELESSSF----------------AFHADHLQEI 220
            :|||:.|||.                  |.|...:|.|:                |.|..::..|
  Fly   171 EKLAEFHAAGAVWRQRKGPFPDDFQRIYLPANYQKSKSYQARLQSYKTAIASWGLADHEQYVSRI 235

  Fly   221 VYCDEATDFYATILDTSVQQALESLGDANADDCLTTPIRLLEELRTNLFENLKHEINATAAAPNS 285
            ...|:....||:..:.:.|:.                                           .
  Fly   236 PTADQFVQSYASCFNNNPQEF-------------------------------------------K 257

  Fly   286 VICHGDLWVNNIMF----RSEPEEVIFFDLQAMRKSSPIFDILHFIYTSTRRPLRDVHTDTLLAA 346
            |:.|||.|.:|||.    ..:..:|.|.|.|..:..||..|:...|..|.|..:|..:.|..:..
  Fly   258 VLNHGDFWSSNIMLSYTQTGDINQVRFVDFQLCKWGSPAQDLWELIICSARHSIRIQYFDYFIRI 322

  Fly   347 YSQALSEELRHQLEDTTAAERLEELCEAFSLQRLSSDYVRQVHYG-LAIGMW------------I 398
            |    ...|...|:....:||:..|              |::|.. :..|.|            :
  Fly   323 Y----HTHLVRCLKILKYSERIPML--------------RELHMSMIKYGFWGYFTTFTHLVFIL 369

  Fly   399 LPAVTFDPNNLPNLDVMSEQNLTGKEIKCTQMLTSEYHMR---------IRELVMEF 446
            ||     |:...:|..:::....|...: :::.|:..::|         :|..:::|
  Fly   370 LP-----PDTEASLVKLTQPGEEGDRFR-SKVYTNPLYVRSALSIFPFLLRRGILDF 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5644	NP_648274.1	EcKinase	65..357	CDD:281023	74/351 (21%)
CG5644	NP_648274.1	P-loop_NTPase	<357..435	CDD:304359	14/90 (16%)
CG31102	NP_001262951.1	EcKinase	50..336	CDD:281023	75/359 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I6679
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910