DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5644 and CG13360

DIOPT Version :9

Sequence 1:	NP_648274.1	Gene:	CG5644 / 39029	FlyBaseID:	FBgn0035948	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_569859.1	Gene:	CG13360 / 31025	FlyBaseID:	FBgn0025620	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	105/460 - (22%)
Similarity:	175/460 - (38%)	Gaps:	120/460 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LRQLFSQSKLVSFSIAHIACSAGSSSGDNYMSVVKRV-TISQAGKDQ-DPELAGSEIVTVIVKRQ 101
            ||.:....|.:.||      .:....|:||.|.:.|. .:.::.|.| |.|||       ::.:.
  Fly    31 LRDMRVDIKKIIFS------ESSGGGGENYCSKIYRAKALYRSSKRQLDEELA-------LIVKS 82

  Fly   102 IASLSRRQLYRCEEAFSNEINAYRHLAPLLAAHSRHQLFPVCHIAESQDRRDAEGG--------- 157
            ||.....|       |..|          ||.:.|.::| ...:....:....:|.
  Fly    83 IAITPATQ-------FLEE----------LAVYLREKIF-YFDVLGKLEVLIGDGSKFGAKCLYT 129

  Fly   158 --EPI--IVLQDLKAMGFRMKDRLAGLELSDCLLVMKKLAQLHAASLAAQELESSSFAFHADHLQ 218
              |||  ||..||...|:::..|.:||....|::::|||.:.||:|:...|.|.|.    .:|
  Fly   130 TREPIQTIVFDDLTQYGYKLASRQSGLNEEHCVVILKKLGKFHASSMVLAEKEPSV----REH-- 188

  Fly   219 EIVYCDEATDFYATILDTSVQQALESLGDANADDCLTTP--------IRLLEELRTNLFENLKHE 275
                      |...:||.:..:..|...:.....|.|..        ..||.|......:|:|..
  Fly   189 ----------FTTGMLDENYIRTNERFINFMTLQCRTLANVVSKWPGYELLAEKLHRHCDNIKEN 243

  Fly   276 INATAAAP----NSVICHGDLWVNNIMFR------SEPEEVIFFDLQAMRKSSPIFDILHFIYTS 330
            : .|...|    .:|:.||||||||.|::      ::|.:.||.|.|.....||..||..|:.:|
  Fly   244 L-VTTGRPLPGEITVLNHGDLWVNNFMYKYDDEQPTKPIDAIFVDFQNSFFGSPGCDINFFLNSS 307

  Fly   331 TRRPLRDVHTDTLLAAYSQALSEELRHQLEDTTAAERLEELCEAFSLQRLSSDYV---------- 385
            .:..:.....:.|:..|..:|.:                      ||:|:.|.:|
  Fly   308 VQLDVLIHRREFLIQTYYASLRD----------------------SLERMHSAFVPSYADIQQEI 350

  Fly   386 --RQVHYGLAIGMWILPAVTF---DPNNLPNLDVMSEQNLTGKEIKCTQMLTSEYHMRIRELVME 445
              |:: ||.......||.||.   |..:: :::.:|:|:...|:::............:|..:..
  Fly   351 RAREL-YGFFSSYAFLPMVTMKKEDSYDI-SIEALSDQDFAKKKVQLMFSSNPRTTDTLRYALRR 413

  Fly   446 FYELG 450
            |.:||
  Fly   414 FDDLG 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5644	NP_648274.1	EcKinase	65..357	CDD:281023	80/324 (25%)
CG5644	NP_648274.1	P-loop_NTPase	<357..435	CDD:304359	16/92 (17%)
CG13360	NP_569859.1	EcKinase	50..335	CDD:281023	82/348 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	4	3.910