DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5644 and E02C12.12

DIOPT Version :9

Sequence 1:	NP_648274.1	Gene:	CG5644 / 39029	FlyBaseID:	FBgn0035948	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_505432.2	Gene:	E02C12.12 / 183991	WormBaseID:	WBGene00017097	Length:	200	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	43/201 - (21%)
Similarity:	72/201 - (35%)	Gaps:	58/201 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 GDN-----------YMSVVKRVTIS----QAGKDQDPELAGSEIVTVIVKRQIASLSRRQLYRCE 114
            |||           :.|::..:...    :.|||...:.|    |.:..:..:|.||:......|
Worm    12 GDNMKATNISDLKGFQSIIALIEPDWIDVEKGKDLPKKFA----VKISTQLALAVLSKIMKLGGE 72

  Fly   115 EAFSNEINAYRHLAPLLA-AHSR------------HQLFPVCHIAESQDRRDAEGGEPIIVLQDL 166
            ..||.|  ....|..|:. .|:|            |...|...:...:...||         .||
Worm    73 NGFSEE--KLNELGKLIRDGHNREVATYKLLEKMNHPDIPYTKVYGLKGYSDA---------NDL 126

  Fly   167 KAMGFRMKDRLAGLE--------LSDCLL-VMKKLAQLHAASLAAQELESSSFAFHADHLQ---E 219
            |  ||.:.:.:..:.        |:|.|: :::.:|...|......| |..:||...::|:   |
Worm   127 K--GFMIMEFIPNVRSIPMYEAILADDLISLVRGIATFAALGETLSE-EEKAFAGGPEYLESMFE 188

  Fly   220 IVYCDE 225
            .|:.||
Worm   189 EVFTDE 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5644	NP_648274.1	EcKinase	65..357	CDD:281023	43/201 (21%)
CG5644	NP_648274.1	P-loop_NTPase	<357..435	CDD:304359
E02C12.12	NP_505432.2	PKc_like	1..>200	CDD:304357	43/201 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433354at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820