Protein Alignment CG5644 and F49C12.7

DIOPT Version :10

• Sequence 1: NP_648274.1
• Gene: CG5644 / 39029
• FlyBaseID: FBgn0035948
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001040948.1
• Gene: F49C12.7 / 177751
• WormBaseID: WBGene00009877
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 439
• Identity: 84/439 - (19%)
• Similarity: 137/439 - (31%)
• Gaps: 145/439 - (33%)

  Fly    60 AGSSSGDNYMSVVKRVTISQAGKDQDPELAGSEIVTVIVKRQIASLSRRQLYRCEEAFSN-EINA 123
            |.|:|.:|...  :|..||:..|  ..|||...:.|.:....:..::.      |.|..| :|..
 Worm    13 AKSNSEENVEK--ERKAISEMLK--TAELADGLLGTTLQWEDVQKIAE------ESAGHNLKIGE 67

  Fly   124 YRHLAPLLAAHSRHQLFPVCHI---AESQDRRDAEG------GEPIIVLQDLKAMGFRMKDRLAG 179
            .:.:.||........|..:..|   .|..|:.....      |.|:.:||.|:|...::...:|.
 Worm    68 KKTIKPLAEGVGLQSLLGIAEIDWEVEGDDKAPYPNKFALKIGSPVALLQALEAQAAKLPPDVAA 132

  Fly   180 LELSDCLLVMKKLAQLHAASLAAQELESSSFAFHADHLQEIVYCDEATDFYATILDTSVQQALES 244
             .:||..:..  |...|           :|..:...::|.:...|...|||       ....:|.
 Worm   133 -NISDEFISF--LPPCH-----------NSENYFYKYIQSLPKLDILPDFY-------FGNQIEL 176

  Fly   245 LGDAN-ADDCLTTPIRLLEELRT---------------------------NLFENLKHE------ 275
            ..|.| :..|:.  |.|:|:::|                           ||.|:.:.|
 Worm   177 EKDGNYSKGCIA--IELVEDIKTLSPLENFSDDQMLQVLDALAKLQVQFINLSEDKRREAPHQGL 239

  Fly   276 -----------------------------INATAAAP-------------------NSVICHGDL 292
                                         :..|.|..                   ..|..||||
 Worm   240 SGLYSPFKDWFLQLNNGLMALFPDPEMQKLTETFATTLPEIITADELDLVPCKLGMKKVFVHGDL 304

  Fly   293 WVNNIMFRSEPEEVIFFDLQAMRKSSPIFDILHFIYTSTRRPLRDVHTDTLLAAYSQALSEELRH 357
            |..|||:..|.......|.|.:.......|:...:.|......|..:.:..|..|...|:   :|
 Worm   305 WSANIMWNQEGHLKKLIDFQMIHFGLAATDLARVMNTCLSPEERHANKEKYLKHYFDCLT---KH 366

  Fly   358 QLEDTTAAERLEELCEAFSLQRLSSDYVRQVHYGLA---IGMWILPAVT 403
            ..||....        .|.|::|::.      |.||   :..::|||:|
 Worm   367 CKEDDHPV--------PFDLEQLTTT------YNLAYPRVSAYLLPALT 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5644	NP_648274.1	EcKL	65..357	CDD:397213	68/383 (18%)
		P-loop containing Nucleoside Triphosphate Hydrolases	<357..435	CDD:476819	13/50 (26%)
F49C12.7	NP_001040948.1	Protein Kinases, catalytic domain	34..408	CDD:473864	76/414 (18%)