Protein Alignment Srp68 and SRP68

DIOPT Version :9

• Sequence 1: NP_648273.1
• Gene: Srp68 / 39028
• FlyBaseID: FBgn0035947
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_015081.1
• Gene: SRP68 / 855833
• SGDID: S000006164
• Length: 599
• Species: Saccharomyces cerevisiae
• Alignment Length: 654
• Identity: 141/654 - (21%)
• Similarity: 244/654 - (37%)
• Gaps: 182/654 - (27%)

  Fly    50 DFQRYRGYCSRRIRRLRKALKYPQGDKRHFKRRDVTIGQLTGKKADERFIHIP---LICAERAWA 111
            ||.:|....:::::.||........|.:.:..:: ..|::..:..|.:...|.   |:.|||..|
Yeast    24 DFAKYHAKLNKKLQHLRSRCHLVTKDTKKYSSKN-KYGEINSEDYDNKTKLIGVLILLHAERDLA 87

  Fly   112 YAMQLK----QESNTEPRKRFHLVNKLRRACFYALQLQELCNTEAFDARTKLECEAYVAWMH--- 169
            .|..||    |....:..:...|..:|::||..|.:|..:...|. ...|:.:..|:...:|
Yeast    88 LAETLKLRARQRGKLKKSEEKVLSTRLKKACKTADKLVNVTQNEQ-QWITRAQYLAFAKLVHSEY 151

  Fly   170 ------------GTLHFELQLWKTAGEHLKR----AQVVYENLGKALPEDEQELYRAKVNEFTPN 218
                        ..:...|.|...|.||||.    |:.|.:|:               ||::..:
Yeast   152 LINGKRFKRKDNAKISNNLALVFAALEHLKNLSLLAEEVVDNI---------------VNKYQYS 201

  Fly   219 LRYCAYNI------------SGGASGGKIDEILELRAQGVLEN-LDVLVSQTKTESSEGLQTIDW 270
            |:..|.|:            ...:...|.||:::|    :|:| .::....|.||..:....|:|
Yeast   202 LKQYAGNLITTPEINNFIVERVQSDENKDDELVKL----LLDNGFNMKKITTSTEDQKVTTNINW 262

  Fly   271 RGRKVTVRPEKVRLFLLSAQELDKSLAKTTKQDAKIELIERIL---------MDCKDAIQAVRDE 326
            |.....:...:|..||  .|.|.....:.|:...::..:|:.|         .|.:|.|    ||
Yeast   263 RSFNAKIIDAEVAQFL--EQGLSIHPTQITQYTQRLSKLEKALDRHEFFIANHDDQDDI----DE 321

  Fly   327 IKQDPKLRSLTTGQTVSGVQYLLAYLSY------IRHSRTLQRNLCLVEQAKLNFYDPNLQSQQN 385
            :.::....:          |.:|||:.|      |...|.|..:| ..:..|||...|:
Yeast   322 MVENSSENN----------QIILAYIKYNILLTSISRERDLFTHL-WNQWLKLNTSLPS------ 369

  Fly   386 VGDGKRVRPQDLARLYEIILQNVTEMQQINGLEDDATYQSEVENLAITFKAFRCYYIALTLIDIK 450
                |..:.:::.|:.:.:.:.::::.::.|:..|....|:::...:.|:.|........|...|
Yeast   370 ----KLTKYKEMERIVKNLTKYLSDIMELPGVYSDDELLSQLDLCKLYFQLFLNTGCLSVLYQSK 430

  Fly   451 -KWKEAVALYERASNYATEALKGKSSPEFQLQEELKKVVSAIDGCKFSAHAYSVLEDDNS----- 509
             ::.||:|||..|..              :|:.:|.::.| :|.....|:..|:    ||
Yeast   431 GRYMEALALYVDAYR--------------RLENKLSEIES-LDEILLPANLLSL----NSVRSLQ 476

  Fly   510 ---EESGTTTKSQKTTKPLYERL----SLYKED----QSLHTK--------APNVFKLTPDMEPI 555
               |..|.:.    .|...||:.    ||.|.|    :.|.:|        ..|:|.|.|.|.||
Yeast   477 KRIENGGNSV----ITLAEYEKRNHGGSLGKYDLTVIEKLDSKKILPTDIQLKNLFPLKPKMLPI 537

  Fly   556 PCKPIFFDLAMTYV----ELPSLEGKLES--------------------PGKKGASITGFVKGFL 596
            |.||..||||..|:    :.||.....:|                    |.||        :|||
Yeast   538 PSKPTLFDLAFNYITYDKQEPSASQVKDSVTETESISQTPISNEQTEGEPKKK--------RGFL 594

  Fly   597 GWGG 600
            |..|
Yeast   595 GLFG 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srp68	NP_648273.1	SRP68	46..568	CDD:293574	129/596 (22%)
SRP68	NP_015081.1	SRP68-RBD	24..551	CDD:419828	129/597 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345215
Domainoid	1	1.000	54	1.000	Domainoid score	I2769
eggNOG	1	0.900	-	-		E1_KOG2460
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1812
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54870
OrthoFinder	1	1.000	-	-		FOG0005221
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102026
Panther	1	1.100	-	-	LDO	PTHR12860
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1392
SonicParanoid	1	1.000	-	-		X3732
TreeFam	0	0.000	Not matched by this tool.
	11	10.920