DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pix and Abce1

DIOPT Version :9

Sequence 1:	NP_648272.1	Gene:	pix / 39027	FlyBaseID:	FBgn0086706	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_001101916.1	Gene:	Abce1 / 361390	RGDID:	1305301	Length:	599	Species:	Rattus norvegicus

Alignment Length:	597	Identity:	462/597 - (77%)
Similarity:	526/597 - (88%)	Gaps:	0/597 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DKQTRIAIVSDDKCKPKRCRQECKKTCPVVRMGKLCIEVTPTSKIASLSEELCIGCGICVKKCPF 75
            ||.||||||:.||||||:|||||||:|||||||||||||||.||||.:||.||||||||:|||||
  Rat     3 DKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPF 67

  Fly    76 EAITIINLPSNLEKHTTHRYSKNSFKLHRLPIPRPGEVLGLVGQNGIGKSTALKILAGKQKPNLG 140
            .|::|:||||||||.|||||..|:|||||||||||||||||||.|||||||||||||||||||||
  Rat    68 GALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLG 132

  Fly   141 KYANPPDWTEILSYFRGSELQNYFTKILEDNLKALVKPQYVDQIPKAVRGAVGDLLDKKDERELQ 205
            ||.:||||.|||:|||||||||||||||||:|||::|||||||||||.:|.||.:||:|||.:.|
  Rat   133 KYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQ 197

  Fly   206 TKICEMLDLSHIRDREIAQLSGGELQRFAIAMVCIQNADIFMFDEPSSYLDVKQRLNAALTIRSL 270
            ..:|:.|||:|:::|.:..||||||||||.|:||||.|||||||||||||||||||.||:|||||
  Rat   198 AVVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSL 262

  Fly   271 LHPTKFIIVVEHDLSVLDYLSDFICCLYGVPGCYGVVTMPFSVREGINIFLDGFVPTENMRFRTE 335
            ::|.::|||||||||||||||||||||||||..||||||||||||||||||||:|||||:|||..
  Rat   263 INPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDA 327

  Fly   336 SLTFKVSESATEEEIKRMNHYVYPAMVKTLGKFELTVEKGHFSDSEILVLLGENGTGKTTFIRML 400
            ||.|||:|:|.|||:|:|..|.||.|.|.:|:|||.:..|.|:||||:|:|||||||||||||||
  Rat   328 SLVFKVAETANEEEVKKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRML 392

  Fly   401 AGNLQPDGEVELPMLNISYKPQKISPKFQNHVRHLLHDKIRDAYVHPQFIADVMKPMKIEEIMDQ 465
            ||.|:||...|:|:||:||||||||||....||.|||:||||||.||||:.|||||::||.|:||
  Rat   393 AGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQ 457

  Fly   466 EVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAKKTGFVVEHDF 530
            |||.|||||||||||.|||||||||||||||||||||||||:||:|:||:|||||||.|||||||
  Rat   458 EVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDF 522

  Fly   531 IMATYLADRVIVIEGQPSVKTTAFSPQSLLNGMNRFLELLGITFRRDPNNFRPRINKNNSVKDTE 595
            ||||||||||||.:|.||..|.|.|||:||.|||:||..|.|||||||||:||||||.||:||.|
  Rat   523 IMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVE 587

  Fly   596 QKRSGQFFFLED 607
            ||:||.:|||:|
  Rat   588 QKKSGNYFFLDD 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pix	NP_648272.1	Rli1	12..605	CDD:224166	458/592 (77%)
Abce1	NP_001101916.1	Rli1	4..597	CDD:224166	458/592 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352789
Domainoid	1	1.000	236	1.000	Domainoid score	I2271
eggNOG	1	0.900	-	-		E1_COG1245
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2205
Inparanoid	1	1.050	959	1.000	Inparanoid score	I313
OMA	1	1.010	-	-		QHG62212
OrthoDB	1	1.010	-	-		D184717at33208
OrthoFinder	1	1.000	-	-		FOG0004228
OrthoInspector	1	1.000	-	-		oto98006
orthoMCL	1	0.900	-	-		OOG6_101314
Panther	1	1.100	-	-	LDO	PTHR19248
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X165
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770