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Protein Alignment CG5026 and MTMR3

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_066576.1	Gene:	MTMR3 / 8897	HGNCID:	7451	Length:	1198	Species:	Homo sapiens

Alignment Length:	624	Identity:	159/624 - (25%)
Similarity:	256/624 - (41%)	Gaps:	140/624 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IKTPKLDGVLLHDPSNAGASGATVGTLCITGHHLLLSARQETSQELWLLHKNIDCVEKKPSLSQN 71
            ::.|.|:   ||..|......|....:.::.:.|.:..::........|.::::|.:    :.|
Human    30 LQVPFLE---LHGESTEFVGRAEDAIIALSNYRLHIKFKESLVNVPLQLIESVECRD----IFQ- 86

  Fly    72 IVVGGIITLKCKDLRIISLEIKCGKEFFNVAASLEALSAIQNTELLYPFFYRPMYSILEDGYTMF 136
                  :.|.|||.::    |:|  :|.......|.|..:.|.                     .
Human    87 ------LHLTCKDCKV----IRC--QFSTFEQCQEWLKRLNNA---------------------I 118

  Fly   137 RPELEFAKLIS----GVGMGGASSPNVANITICMPSTSTSTLTVGAGIPHPLQNGYAIEALACGV 197
            ||..:...|.|    ...|...:|....:..:|.|         |..:....:|  .:|.:...:
Human   119 RPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRP---------GEHVTSRFKN--EVERMGFDM 172

  Fly   198 GGVGGGALQSPQASCEWRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSYR 262
            ...             |||:|:|..:.:|.:|...||||..|||:::...::||...|.|.:.||
Human   173 NNA-------------WRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYR 224

  Fly   263 HE-NGATLMRSSQP-LS------------IQGI-KRCRA-------------------------- 286
            |: |||.:.|..|| :|            :|.: |.|.:
Human   225 HQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSD 289

  Fly   287 ---DEAILN--------------LVLGRSRKGFIVDTWGKGKSNTETDLHYSQWKKVNRSIGNVS 334
               |.::.|              |:|........|....|| ...|...:|...:.|...:.|:.
Human   290 VEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKG-GGCECPEYYPNCEVVFMGMANIH 353

  Fly   335 SPASILDSFARLIEACNDLGCSTDKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGA 399
               ||..||..|...|..:. ....|||.||::.||..:...|.::.:|...:||:..|||||.:
Human   354 ---SIRRSFQSLRLLCTQMP-DPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCS 414

  Fly   400 KGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFASRHRYSC-YTPNQTRNKTSGAT 463
            .|.|.|..:.:|.:::|:|..||:.|.|.|:|.||:..||.||.|    | :..|..........
Human   415 DGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADR----CGHGENSDDLNERCPV 475

  Fly   464 FVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSLWSYL 528
            |:.:|||::||..||||||||:...|:.|.:|::...:|||||::.:||.|.:...||.|:||.|
Human   476 FLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLL 540

  Fly   529 NRPDVLQTFLNPLYEPNAN-VIWPSVAPISLELWSDLYL 566
            ...:  :.|.|.||...:. |::|.....:|.|||.:||
Human   541 RAGN--KAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYL 577

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.