Protein Alignment CG5026 and YMR1

DIOPT Version :10

• Sequence 1: NP_648271.3
• Gene: CG5026 / 39026
• FlyBaseID: FBgn0035945
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_012644.1
• Gene: YMR1 / 853574
• SGDID: S000003871
• Length: 688
• Species: Saccharomyces cerevisiae
• Alignment Length: 720
• Identity: 173/720 - (24%)
• Similarity: 255/720 - (35%)
• Gaps: 234/720 - (32%)

  Fly     1 MEFADLIKTPKLDGVLLHDPSNAGASGATVGTLCITGHHLLLSARQETSQELWLLHKNIDCVEKK 65
            ||:   ||..|:..|:||....     ||.|||.:|.|||:..:.| .|.|.|..:..|..|.|.
Yeast     1 MEY---IKIAKVSNVVLHRRGT-----ATQGTLHLTTHHLIFESPQ-LSTEFWFPYPLIYGVHKN 56

  Fly    66 P------------------------SLSQNIVVGGIITLKC--KDLRIISLEIKCGKEFF----N 100
            |                        .|.|...:...:.:|.  ||..:.||:.  |.:..    .
Yeast    57 PGSTLLSKLTSTNQIQLEGTDSQNYKLYQGKDLWSFVNIKVIGKDYAVFSLDF--GGDLHLQARK 119

  Fly   101 VAASLEALSAIQNTELLYPFFY------RPMYSILEDGYTMFRPELEFAKLISGVGMGGASSPNV 159
            |..|:..|:.:.|...||.|.|      |.:.|  .|.:.::.|..||.:
Yeast   120 VYDSILNLTVLSNITQLYAFIYISNNLERKLPS--PDSWDIYDPIKEFRR--------------- 167

  Fly   160 ANITICMPSTSTSTLTVGAGIPHPLQNGYAIEALACGVGGVGGGALQSPQASCEWRITNVNRDFS 224
                                                       ..|.|...:|.||::.||..:.
Yeast   168 -------------------------------------------QGLDSKDETCPWRLSTVNEHYE 189

  Fly   225 VCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSYRHE-NGATLMRSSQPL-------SIQGI 281
            .|.||.:.|.||::.:|..:..::.||...|.|||:|.|: ....::||||||       |||..
Yeast   190 FCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDE 254

  Fly   282 KR--------CRAD---------------EAILNLVLGRSRKG------FIVD-TWGKGKSNTET 316
            |.        |..|               .|:..:.||...:.      |:.| ..|..||
Yeast   255 KLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKS---- 315

  Fly   317 DLHYSQWKKVNRSIGNVSSPASILDSFARLIEACNDLGCSTDKWLSRLEN-SGWL---SLVLNSL 377
             |......::...|.|:...::.......:|....||....::.|.|.:. |.||   :|:|.|:
Yeast   316 -LKLPTVTRLFLGIDNIHIVSNTAAYMTEVICQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSV 379

  Fly   378 NASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFA 442
            :   ::.:.:....|.||||.:.|.|.|..|.||::|.|:|..||..|...|:|::|...||.|.
Yeast   380 D---MLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFL 441

  Fly   443 SRHRY--------------------------------------------------------SCYT 451
            .|..:                                                        ..:.
Yeast   442 ERSGHLNSDIRFHDNTMHSNFNDVDTNGDDLDIGVNTQDDYAEDDEGGEDETNLINLSRISKKFN 506

  Fly   452 PNQTRNKTS----GATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERER 512
            .|...||.|    ...|..||||:|||.||.|..|||:.:.|..|..|.:..||||||.:||:|:
Yeast   507 ENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEK 571

  Fly   513 NELNVHTRTTSLWSYLNRPDVLQTFLNPLY---------------EPNANVIWPSVAPISLELWS 562
            .:.|:..:|.|:|.|..  ...:.|:||.:               |....|.|.|.....::.|.
Yeast   572 FQQNLPNKTKSVWDYFR--SRRKQFINPNFIQRKRSGMNEHDQNLEEEEKVEWISPDLKKVQWWW 634

  Fly   563 DLYLR 567
            .||.|
Yeast   635 QLYGR 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_648271.3	PH-GRAM_MTMR9	1..106	CDD:275398	35/134 (26%)
		Myotub-related	210..512	CDD:461958	107/403 (27%)
YMR1	NP_012644.1	PH-like	1..>44	CDD:473070	20/51 (39%)
		Myotub-related	152..570	CDD:461958	114/485 (24%)