DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5026 and MTM2

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_196074.2	Gene:	MTM2 / 830333	AraportID:	AT5G04540	Length:	833	Species:	Arabidopsis thaliana

Alignment Length:	492	Identity:	137/492 - (27%)
Similarity:	226/492 - (45%)	Gaps:	98/492 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 WRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSYRHE-NGATLMRSSQPL- 276
            |||||:|.::.:|.:|...|:|||:|:||:::.::.||...|.||:|:.|. :||.:.||||||
plant   219 WRITNLNSNYDLCQSYPFALMVPKSISDEELLQTSTFRARCRLPVISWCHPGSGAVIARSSQPLV 283

  Fly   277 SIQGIKRCRADEAILNLVL-------GRSRKGFIVD---------TWGKGKSNTETDLHYSQWKK 325
            .:....|..:||.::....       |..||.:|||         ...|| ..:|:..:|.|.:.
plant   284 GLMMNMRSNSDEKLVASFCTQLAGHKGARRKLYIVDARPRKNALANGAKG-GGSESSSNYLQSEI 347

  Fly   326 VNRSIGNVSSPASILDSFARLIEACNDLGCSTD------------KW-----------LSRLENS 367
            |...|.|:.   ::.:||:||.:..:..|.::.            .|           :|.|.:|
plant   348 VFLGIDNIH---AMRESFSRLRDYLDMHGTTSSDGTSSFLRHGGWTWGGGNLSSMSASVSVLGDS 409

  Fly   368 GWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIER 432
            ||||.:.:.|.....:|..:..|.:.||||.:.|.|.|..:.||..::|:|..||..|.|||:|:
plant   410 GWLSHIQSILAGVAWIAARVAMESASVLVHCSDGWDRTTQLVSLACLLLDPYYRTFSGFQALVEK 474

  Fly   433 EWIQAGHPFASRHRYSCYTPN---------------------------------QTRNKTSGAT- 463
            :|:..||||:.|    ...||                                 |:.:.:.|..
plant   475 DWLSFGHPFSDR----VGMPNVSESGNFELPIQSSSARSFPSSPVRQSPGSAAAQSSSSSYGLNN 535

  Fly   464 ----FVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSL 524
                |:.:||||.||...:|.:||||...|:...:.....::|.|||:||:||.:..:......:
plant   536 YSPIFLQWLDCISQLMRMYPSAFEFSPTFLVDFIDCLLSCRFGNFLCNSEKERQQCGISETCGCI 600

  Fly   525 WSYL----NRPDVLQTFLNPLYEPNA--NVIWPSVAPISLELWSDLYLRWVIDQRSSVT-VMSQI 582
            |:||    :.........||.|:|:.  ..:.|..|.::..||...:|||......:|| ...|.
plant   601 WAYLADLRSSSGTSHVHCNPFYDPSRYDGPLLPPAAALAPTLWPQFHLRWACPVEPNVTETEDQC 665

  Fly   583 QELVTREKELRTQALKLRKQAMELGQEVSNLMKSGND 619
            :.:..:..|::    |.:::|.....|:|:.|:|.|:
plant   666 RAMTVKYSEMK----KEKEEAERKVDELSSAMESLNE 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	110/375 (29%)
MTM2	NP_196074.2	GRAM	49..108	CDD:214725
MTM2	NP_196074.2	Myotub-related	168..587	CDD:284109	110/375 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10807
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020