DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5026 and Sbf1

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_006521601.1	Gene:	Sbf1 / 77980	MGIID:	1925230	Length:	1901	Species:	Mus musculus

Alignment Length:	536	Identity:	138/536 - (25%)
Similarity:	210/536 - (39%)	Gaps:	158/536 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 STLTVGAGI-PHPLQNGYAIEALAC--GVGGVGGGALQS--PQASCE-WRITNVNRDFSVCATYG 230
            ||||..:.: |.......::...||  ....:|.|.|.|  .:|..| :||:.|||.:::|.:|.
Mouse  1110 STLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYP 1174

  Fly   231 ATLIVPKAITDEQIV-LSAAFRDGGRFPVLSYRH-ENGATLMRSS-----------------QPL 276
            ..||||::|.|..:. :|..:|. .||||:.:|. .:.|.|:||.                 .|.
Mouse  1175 GLLIVPQSIQDNALQRVSRCYRQ-NRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNTPSPG 1238

  Fly   277 SIQGIKRCRADEAILNLVLGRSRKGFIVDTWGKGKSNTETDLHY--------------------- 320
            ..|........|..|..|:....:  ..|:.|:...::.:..|.
Mouse  1239 QAQADSSSLEQEKYLQAVVSSMPR--YADSSGRNTLSSFSSAHMGGHVPSPRARVTTLSNPLAAS 1301

  Fly   321 --------SQWKKVNRS---------IGN-------VSSP------------------------- 336
                    .:|..|..|         :|:       :|:|
Mouse  1302 ASRWTASRGKWSSVRASGRSSGLGSDVGSRLAGRDLLSTPHTNGAPPDSGFLRPQRAALYIIGDK 1366

  Fly   337 ------------------------ASILDSFARLIEACNDLGC-----STDKWLSRLENSGWLSL 372
                                    ..:..||.:|::||.. ||     |...:|..||:|.||..
Mouse  1367 AQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVP-GCPATEPSPASFLRSLEDSEWLIQ 1430

  Fly   373 VLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQA 437
            :...|..|.:|.:.|| .||.|||....|.|.|..|.||||::.:|..||:.|.:.|:|:||:..
Mouse  1431 IHKLLQISVLVVELLD-SGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSF 1494

  Fly   438 GHPFASRHRYSCYTPNQTRNKTSGAT--FVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQ 500
            ||.|:.|..::      ...::||.|  |:.||||::|::.|||..||||...|..|..|....:
Mouse  1495 GHRFSHRGAHT------LAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHTSRR 1553

  Fly   501 YGTFLCDSERERNELNV----------HTRTTSLWSYLNR-----PDVLQTFLNPLYEP-NANVI 549
            :.|||.||:.||.||.:          .....|:|.|::|     |    .|.|..|.| :..|:
Mouse  1554 FRTFLLDSDYERIELGLLYEEKGERRGQLACKSVWEYVDRLSKRTP----MFYNYTYAPEDTEVL 1614

  Fly   550 WPSVAPISLELWSDLY 565
            .|.....:|::| |.|
Mouse  1615 RPYSNVSNLKVW-DFY 1629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	119/464 (26%)
Sbf1	XP_006521601.1	uDENN	1..86	CDD:214824
		DENN	129..318	CDD:214823
		dDENN	372..440	CDD:129037
		SBF2	551..772	CDD:372054
		PH-like	901..1019	CDD:388408
		PTP_DSP_cys	1158..1530	CDD:391942	91/382 (24%)
		PH_Sbf1_hMTMR5	1794..1899	CDD:269941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846057
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840