DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5026 and Sbf2

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_008758019.1	Gene:	Sbf2 / 691042	RGDID:	1588657	Length:	1904	Species:	Rattus norvegicus

Alignment Length:	534	Identity:	122/534 - (22%)
Similarity:	201/534 - (37%)	Gaps:	179/534 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 GVGGVGGGALQS-PQASCEWRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVL 259
            |:|.:.|.:.:| |:   .:|:|..||.:|:|.:|...|::|:|:.|..:...|......|.||:
  Rat  1120 GLGTISGSSSRSKPE---YFRVTASNRLYSLCRSYPGLLVIPQAVQDSSLPRVARCYRHNRLPVV 1181

  Fly   260 SYRHENGATLM------------------RSSQPLSIQGIKRCRADE------AILNLVL----- 295
            .:::....||:                  .|.|.:|...::...:.|      |:|..|:
  Rat  1182 CWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVIVHQKL 1246

  Fly   296 ----------------GRSRKGFIVDT-----------------WGKG--------------KSN 313
                            |..|:...:.|                 :.:|              ||:
  Rat  1247 RGNSTLTVRPTLALSPGTERRSSRMSTVLKQVVPGHLDVNPSNSFARGVHGYRDKCFTQSNSKSS 1311

  Fly   314 TETDLH-YSQWKKVNRSIGNVSSPASILD------------------------------------ 341
            .:..:| ...|..:..|...:|||.|::|
  Rat  1312 AKEPVHNQGVWASLRSSTRLISSPTSLIDVGARLAGKDHSASFSNSTYLQNQLSKRQAALYIFGE 1376

  Fly   342 ------------------------------SFARLIEACNDLGCSTDK---WLSRLENSGWLSLV 373
                                          ||.:|:.||......||.   :|..||:|.|...:
  Rat  1377 KSQLRSSKVEFAFNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALEDSEWFPQL 1441

  Fly   374 LNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAG 438
            ...:..:.||::.| :.||.|.|...:|.|.|..||||||::.:|..||:.|.:.|:|:||:..|
  Rat  1442 HRIMQLAVVVSEVL-ENGSSVWVCLEEGWDITTQVTSLVQLLSDPFYRTIEGFRMLVEKEWLSFG 1505

  Fly   439 HPFASRHRYSCYTPNQTRNKTSG--ATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQY 501
            |.|:.|...:      ..::.||  ..|:.||||::|::.|:|..|||:...|..|..|...:::
  Rat  1506 HKFSQRSSLA------LNSQGSGFAPIFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRF 1564

  Fly   502 GTFLCDSERERNELNV--------HTRT-TSLWSYLNR-----PDVLQTFLNPLYEP-NANVIWP 551
            .|||.||:.||.|...        |.:. ..:|..:::     |    .|.|.||.| ....:.|
  Rat  1565 KTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECIDKMHKRSP----VFFNYLYSPVEIEALKP 1625

  Fly   552 SVAPISLELWSDLY 565
            :|...||:.| |.|
  Rat  1626 NVNVSSLKKW-DYY 1638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	104/463 (22%)
Sbf2	XP_008758019.1	uDENN	1..86	CDD:214824
		DENN	115..297	CDD:280329
		dDENN	351..419	CDD:129037
		SBF2	530..752	CDD:289132
		PH-GRAM_MTMR13	880..998	CDD:275416
		Myotub-related	1114..1574	CDD:284109	104/463 (22%)
		PH_Sbf1_hMTMR5	1797..1902	CDD:269941
		PH	1802..1902	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840