Protein Alignment CG5026 and MTMR9

DIOPT Version :9

• Sequence 1: NP_001163392.1
• Gene: CG5026 / 39026
• FlyBaseID: FBgn0035945
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_056273.2
• Gene: MTMR9 / 66036
• HGNCID: 14596
• Length: 549
• Species: Homo sapiens
• Alignment Length: 624
• Identity: 271/624 - (43%)
• Similarity: 373/624 - (59%)
• Gaps: 97/624 - (15%)

  Fly     1 MEFADLIKTPKLDGVLLHDPSNAGASGATVGTLCITGHHLLLSARQETSQELWLLHKNIDCVEKK 65
            ||||:|||||::|.|:||.|...    |..||||:|||||:||:||:.::||||||.|||.::|:
Human     1 MEFAELIKTPRVDNVVLHRPFYP----AVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKR 61

  Fly    66 PSLSQNIVVG--GIITLKCKDLRIISLEIKCGKEFFNVAASLEALSAIQNTELLYPFFYRPMYSI 128
                   .||  |.|.:||||.|||.|:|...:|..|:|:|:||||.:.:..|:||||||||:.:
Human    62 -------FVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEV 119

  Fly   129 LEDGYTMFRPELEFAKLISGVGMGGASSPNVANITICMPSTSTSTLTVGAGIPHPLQNGYAIEAL 193
            :|||:..|.||.||.                      :.|::||
Human   120 IEDGWHSFLPEQEFE----------------------LYSSATS--------------------- 141

  Fly   194 ACGVGGVGGGALQSPQASCEWRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPV 258
                               |||::.||::|:||.:|...:.|||:|.||.:...|.||.||||||
Human   142 -------------------EWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGRFPV 187

  Fly   259 LSYRH-ENGATLMRSSQPLSIQGIKRCRADEAILNLVLGRSRKGFIVD---------TWGKGKSN 313
            |||.| :||..:|||.|||:....:||:.||.::|..|...::|:|:|         |..|| ..
Human   188 LSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRSLNVAQQTRAKG-GG 251

  Fly   314 TETDLHYSQWKKVNRSIGNVSSPASILDSFARLIEACNDLGCSTDKWLSRLENSGWLSLVLNSLN 378
            .|.:.||.||:::::||....   .:.:|..:|:|||||...:.|:|||:||.|.||:.:...|.
Human   252 FEQEAHYPQWRRIHKSIERYH---ILQESLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILT 313

  Fly   379 ASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFAS 443
            .:|:.|||:|:||:.:|:||.:|.||||.||||.||||.|..||:||.:|||||||:||||||..
Human   314 TACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQ 378

  Fly   444 RHRYSCYTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDS 508
            |...|.|.  .|:.|.....|:|||||::|:..||||||||:...||:||||::.||:||||.::
Human   379 RCAQSAYC--NTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNN 441

  Fly   509 ERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLYEPNANVIWPSVAPISLELWSDLYLRWVIDQR 573
            |.||.:|.:..:|.||||::|:|..|..|.|||:|.|..||||||||.||.||..::|||   .|
Human   442 ESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEANNLVIWPSVAPQSLPLWEGIFLRW---NR 503

  Fly   574 SSVTVMSQIQELVT---REKELRTQALKLRKQAMELGQE 609
            ||..:....:|:|.   ..|||:.:...||:|..||..|
Human   504 SSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETE 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398	55/106 (52%)
		Myotub-related	117..511	CDD:284109	165/403 (41%)
MTMR9	NP_056273.2	PH-GRAM_MTMR9	1..97	CDD:275398	55/106 (52%)
		Myotub-related	127..446	CDD:310891	155/386 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155616
Domainoid	1	1.000	342	1.000	Domainoid score	I1080
eggNOG	1	0.900	-	-		E1_KOG1089
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9148
Inparanoid	1	1.050	525	1.000	Inparanoid score	I1249
Isobase	1	0.950	-	0	Normalized mean entropy	S2030
OMA	1	1.010	-	-		QHG47990
OrthoDB	1	1.010	-	-		D192248at33208
OrthoFinder	1	1.000	-	-		FOG0006594
OrthoInspector	1	1.000	-	-		oto89545
orthoMCL	1	0.900	-	-		OOG6_106188
Panther	1	1.100	-	-	LDO	PTHR10807
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4020
SonicParanoid	1	1.000	-	-		X4139
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750