DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5026 and sbf1

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_009298445.1	Gene:	sbf1 / 568277	ZFINID:	ZDB-GENE-040718-139	Length:	1936	Species:	Danio rerio

Alignment Length:	642	Identity:	151/642 - (23%)
Similarity:	243/642 - (37%)	Gaps:	221/642 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 PSTSTSTLTVGAGIPHPLQNGYAIEALAC------GVGGVGGGALQSPQASCEWRITNVNRDFSV 225
            ||:.|.:.|:.:.....:.|  .:|...|      |:|.:.....:|...  .:||:.|||.::|
Zfish  1116 PSSLTLSSTIRSSDRQTMSN--VVERACCRDYQRLGLGTLSNSLTRSKNE--PFRISTVNRMYTV 1176

  Fly   226 CATYGATLIVPKAITDEQIV-LSAAFRDGGRFPVLSYRHENGATLMRSSQPLSIQGI-------- 281
            |.:|...||||::|.|..|. :...:|. .||||:.:|:.....::..|..|..:|:
Zfish  1177 CRSYPGLLIVPQSIPDSTIQRICRCYRQ-NRFPVVCWRNSRTKAVLLRSAGLHAKGVVGFFKSPN 1240

  Fly   282 ----KRCRADE---------------------------------------------------AIL 291
                ...:||.                                                   |::
Zfish  1241 APTAGPSQADSTSLEQEKYLQAIISSMPSYSETSGRNTLSGFTSSHMSTSDSSDKLRQPKIGALM 1305

  Fly   292 NLVLG---------------------------------RSRKGFIVDTWGK-------------- 309
            ..|:|                                 .|.:|    .||.
Zfish  1306 KQVMGAKEDVPGTFSRGALGQRARVVSLSQPRVSVKARNSPRG----KWGSIRGSGRLSTYNPDV 1366

  Fly   310 --------------GKSNT---------------ETDL------HYSQWKKVNRSIGNVSSPASI 339
                          |.|.|               ::.|      .:.||:.|...:.:|   ..:
Zfish  1367 GNRLAGKESPQANGGPSETYFLRQQRAYLFIIGDKSQLKGGKQDSFQQWEVVPIEVFDV---RQV 1428

  Fly   340 LDSFARLIEACNDLGCSTDKWLS---RLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKG 401
            .:||.:|::||.....|.|..::   .||.|.|::|:...|..|.:|.:.|| .||.|:|....|
Zfish  1429 KNSFKKLMKACVPSSLSFDANMTFHRCLEESEWMNLLHRVLQVSVLVVELLD-NGSSVMVSLEDG 1492

  Fly   402 LDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFASRHRYSCYTPNQT-RNKTSGAT-- 463
            .|.|..|.||||::.:|..||:.|.:.|:|:||:..||.|:  ||.:     || .:::||.|
Zfish  1493 WDVTTQVVSLVQLLSDPYYRTIDGFRLLVEKEWLSFGHRFS--HRGA-----QTLASQSSGFTPV 1550

  Fly   464 FVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNV------HTRTT 522
            |:.||||::|::.|||..||||...|..|..|...:::.|||.||:.||.||.|      ..::|
Zfish  1551 FLQFLDCVHQIHLQFPMEFEFSQYYLKFLAYHYVSNRFRTFLLDSDYERIELGVLYEEKGERKST 1615

  Fly   523 ----SLWSYLNRPD-VLQTFLNPLYEP-NANVIWPSVAPISLELWSDLYLRWVIDQRSSVTVMSQ 581
                |:|.|::|.: ....|.|.::.| ...|:.|.....:|::| |.|....:.:..|..
Zfish  1616 QVCKSVWDYIDRLNKKTPIFYNYMFSPEEEEVLKPYSFVSNLKVW-DFYTEETLSEGPSFD---- 1675

  Fly   582 IQELVTREKE---------LRTQALKLRKQAM----------------ELGQEVSNL 613
             .|||...:|         ..|.|.|.:::.:                :|.|:|.||
Zfish  1676 -WELVQGRQEKPQEEAGDKQETTAPKSKRRIVWPCYDNLSKVVPDAITKLLQDVQNL 1731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	119/501 (24%)
sbf1	XP_009298445.1	uDENN	1..86	CDD:214824
		DENN	117..327	CDD:280329
		dDENN	381..449	CDD:129037
		SBF2	560..782	CDD:289132
		PH-GRAM_MTMR5	910..1027	CDD:275417
		Myotub-related	1143..1598	CDD:284109	112/472 (24%)
		PH_Sbf1_hMTMR5	1829..1934	CDD:269941
		PH	1834..1934	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590788
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840