Protein Alignment CG5026 and MTM1

DIOPT Version :9

• Sequence 1: NP_001163392.1
• Gene: CG5026 / 39026
• FlyBaseID: FBgn0035945
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: XP_011529473.1
• Gene: MTM1 / 4534
• HGNCID: 7448
• Length: 618
• Species: Homo sapiens
• Alignment Length: 662
• Identity: 178/662 - (26%)
• Similarity: 277/662 - (41%)
• Gaps: 170/662 - (25%)

  Fly    10 PKLDG-VLLHD-------PSNAGASGATVGTLCITGHHLLLSARQETSQELWLLHKNID-CVEKK 65
            |:|.| .|:.|       |.|    |...|.:.||.:.|.|.: .||....|..  .:| |:.:.
Human    36 PRLPGETLITDKEVIYICPFN----GPIKGRVYITNYRLYLRS-LETLSSHWRF--EVDTCLFQD 93

  Fly    66 PSLSQNIVVGGI------------------ITLKCKDLRIISLEIK----CGKEFFNVAASLEAL 108
            .||..::.:|.|                  :.:.|||:|.:...:|    ..::.|.:.
Human    94 SSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEIL------ 152

  Fly   109 SAIQNTELLYPFFYR-PMYSILE------DGYTMFRPELEFAKLISGVGMGGASSPNVANITICM 166
                 |...:|..:. |:::.|.      ||:|::.|..|:.:
Human   153 -----TRYAFPLAHSLPLFAFLNEEKFNVDGWTVYNPVEEYRR---------------------- 190

  Fly   167 PSTSTSTLTVGAGIPHPLQNGYAIEALACGVGGVGGGALQSPQASCEWRITNVNRDFSVCATYGA 231
                       .|:|:.                             .||||.:|:.:.:|.||.|
Human   191 -----------QGLPNH-----------------------------HWRITFINKCYELCDTYPA 215

  Fly   232 TLIVPKAITDEQIVLSAAFRDGGRFPVLSYRH-ENGATLMRSSQPLSIQGIKRCRADEAILNLVL 295
            .|:||...:|:.:...|.||...|.||||:.| ||...::|.||||.....||.:.||..|:::.
Human   216 LLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIR 280

  Fly   296 GRSR---KGFIVD------------TWGKGKSNTETDLHYSQWKKVNRSIGNV----SSPASILD 341
            ..::   |..|.|            |.|    ..|:|..|...:.....|.|:    .|...:.|
Human   281 ETNKQISKLTIYDARPSVNAVANKATGG----GYESDDAYHNAELFFLDIHNIHVMRESLKKVKD 341

  Fly   342 SFARLIEACNDLGCSTDKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTL 406
            .....:|..:        |||.||::.||..:...|..:..||..:....|.||||.:.|.|.|.
Human   342 IVYPNVEESH--------WLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTA 398

  Fly   407 IVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFASRHRYSCYTPNQTRNKTS---GATFVLFL 468
            .:|||..::|:...|::.|.:.|:::|||..||.||||..:.      .:|.|.   ...|:.|:
Human   399 QLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASRIGHG------DKNHTDADRSPIFLQFI 457

  Fly   469 DCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFL--CDSERERNELNVHTRTTSLWSYLNRP 531
            ||::|:..|||.:|||:.|.||::.:|.:..::||||  |:|.|||.:  |..||.||||.:|..
Human   458 DCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFLFNCESARERQK--VTERTVSLWSLINSN 520

  Fly   532 DVLQTFLNPLYEPNAN-VIWPSVAPISLELWSDLYLRW--VIDQRSSVTVMSQIQELVTREKEL- 592
            .  :.|.||.|....| |::|..:...||||.:.|:||  .|.|:....|..:..||:....|.
Human   521 K--EKFKNPFYTKEINRVLYPVASMRHLELWVNYYIRWNPRIKQQQPNPVEQRYMELLALRDEYI 583

  Fly   593 -RTQALKLRKQA 603
             |.:.|:|...|
Human   584 KRLEELQLANSA 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398	28/126 (22%)
		Myotub-related	117..511	CDD:284109	114/425 (27%)
MTM1	XP_011529473.1	PH-like	44..158	CDD:302622	25/131 (19%)
		Myotub-related	165..498	CDD:284109	110/412 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850