DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5026 and Sbf

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_477401.2	Gene:	Sbf / 41427	FlyBaseID:	FBgn0025802	Length:	1993	Species:	Drosophila melanogaster

Alignment Length:	542	Identity:	124/542 - (22%)
Similarity:	204/542 - (37%)	Gaps:	151/542 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 WRITNVNRDFSVCATYGATLIVPKAITDEQIV-LSAAFRDGGRFPVLSYRHENGATLMRSSQPLS 277
            :||:|.|..::.|.:|.|.::.|...:|..|: |...|: |.|.|:.::||.|||.|:|..||.|
  Fly  1179 FRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFK-GQRIPLPTWRHANGALLIRGGQPNS 1242

  Fly   278 IQGIKRCR------------------ADEAILNLV------------------------------ 294
            ...|...:                  .|:..|.|:
  Fly  1243 KSVIGMLKNTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSS 1307

  Fly   295 ---------LGRSRK-------GFIVDTWGKG---KSNTETDLHYSQWKKVNRSIGNVSSPASIL 340
                     |.|..|       |......|||   |.|.:..|.:...|....::|..|...|.:
  Fly  1308 DDRQPLTPELSRKHKNNLDISDGNKSSQGGKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNM 1372

  Fly   341 D--------------------SFARLIEAC----NDLGCSTDKWLSRLENSGWLSLVLNSLNASC 381
            :                    :|.:||.||    |........:...:|.|.||..:.:.:..|.
  Fly  1373 NVDFCADFIPVDYPDIRQSRPAFKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSG 1437

  Fly   382 VVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFASRHR 446
            .|...:|.:.|.|::....|.|.|..::|:.|:.|:|..|::.|.:.|:|:||:..||.||  ||
  Fly  1438 AVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFA--HR 1500

  Fly   447 YSCYTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERE 511
            .:....:...|.....||:.|||.::||..|||.:|||:...|..|..||...::.|||.|.|.|
  Fly  1501 SNLKPSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELE 1565

  Fly   512 RNE-------------------------------------LNVHTRTT---------SLWSYLNR 530
            |::                                     |::.::..         |::.|:.|
  Fly  1566 RSDSGIAAMEDKRGSLNAKHMFGAGGMATNGSDDECSVYPLDIRSQRAPAPLNRIGHSIFDYIER 1630

  Fly   531 P-DVLQTFLNPLYEPNANV-IWPSVAPISLELWSDLYLRWVIDQRSSVTVMSQIQELVTREKELR 593
            . :....|.|.||..:.:| :.|.....:|:||. .|....:.|.:...:     |:.|.:.|:.
  Fly  1631 QHNKTPIFYNFLYSGDKSVTLRPQNNVAALDLWC-YYTNEELAQGAPYDL-----EVTTVDDEID 1689

  Fly   594 TQALKLRKQAMELGQEVSNLMK 615
            ....|.::..:..|.:  |:.|
  Fly  1690 LSETKGKRMVITAGYD--NMEK 1709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	100/388 (26%)
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:280329
		dDENN	384..452	CDD:129037
		SBF2	585..807	CDD:289132
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396
		Myotub-related	1161..1565	CDD:284109	100/388 (26%)
		C1	1791..1838	CDD:237996
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941
		PH	1891..1992	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462315
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10807
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940