Protein Alignment CG5026 and mtmr6

DIOPT Version :10

• Sequence 1: NP_648271.3
• Gene: CG5026 / 39026
• FlyBaseID: FBgn0035945
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_956085.1
• Gene: mtmr6 / 327346
• ZFINID: ZDB-GENE-030131-5557
• Length: 643
• Species: Danio rerio
• Alignment Length: 639
• Identity: 199/639 - (31%)
• Similarity: 299/639 - (46%)
• Gaps: 125/639 - (19%)

  Fly     7 IKTPKLDGVLLHDP-SNAGASGATVGTLCITGHHLLLSARQET-SQELWLLHKNIDCVEKKPSLS 69
            |:|||::.|.|.|. ||.    :..|||.:|..||:......| |||:|:||.:|..|||. ||:
Zfish     4 IRTPKVEQVKLLDRFSNK----SVTGTLHLTATHLIFVENNSTSSQEIWILHHHIAPVEKL-SLT 63

  Fly    70 QNIVVGGIITLKCKDLRIISLEIKCGKEFFNVAASLEALSAIQNTELLYPFFYRPMYS--ILEDG 132
               ..|..:.::|::.|::...|...::..::.:||..|....:.:.||.|.|.|..:  ..|:|
Zfish    64 ---TTGCPLLIQCRNFRVVHFVIPRERDCHDIYSSLLRLLRPVSYDELYAFSYNPKQNDQQREEG 125

  Fly   133 YTMFRPELEFAKLISGVGMGGASSPNVANITICMPSTSTSTLTVGAGIPHPLQNGYAIEALACGV 197
            :.:.....||.::                                 |:|
Zfish   126 WQLIDLAAEFERM---------------------------------GVP---------------- 141

  Fly   198 GGVGGGALQSPQASC-EWRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSY 261
                          | :|::|:||||:.||.||...|.||...:...||.|:.||..||||||:|
Zfish   142 --------------CDQWQLTDVNRDYKVCETYPRDLYVPITASKPIIVGSSKFRSKGRFPVLTY 192

  Fly   262 RH-ENGATLMRSSQPLSIQGIK-RCRADEAILNLVL---GRSRKGFIVDT-----------WGKG 310
            .: |..|.:.|.|||||  |.. ||..||.:|..:.   ..||..:::||           .|||
Zfish   193 FYQEKKAAVCRCSQPLS--GFSARCLEDEHMLQAISKANHNSRNIYVMDTRPKLNALANRAAGKG 255

  Fly   311 KSNTETDLHYSQWKKVNRSIGNVSSPASILDSFARLIEACNDLGCSTDKWLSRLENSGWLSLVLN 375
            ..|.:   :||..:.....|.|:.   .:..|..:|:|.......|...:|..|||||||..:..
Zfish   256 YENED---NYSNIRFQFVGIENIH---VMRGSLQKLLEVVGTRSLSMTDYLVGLENSGWLRHIKA 314

  Fly   376 SLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHP 440
            .::|:..:|:.:..||:.||||.:.|.|.|..|.:|..::::|..||::|...|||::||..||.
Zfish   315 IMDAAIFLAKAVSVEGASVLVHCSDGWDRTAQVCALGSLLMDPYYRTIKGFMVLIEKDWISFGHK 379

  Fly   441 FASRHRYSC--YTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGT 503
            ||.|    |  ..|:.   |.....|..||:|::||..|||.:||||...||.:.||.|..|:|.
Zfish   380 FADR----CDQLDPDP---KEVSPIFTQFLECVWQLTEQFPQAFEFSEWFLIQIHEHIHSCQFGN 437

  Fly   504 FLCDSERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLYEP----NANVIWPSVAPISLELWSDL 564
            ||.:|:|:|.:|.:..||.|||::|....  |.:|||:|.|    :..|:.||......:.|.::
Zfish   438 FLGNSQRQREDLQLKERTYSLWAHLLSEK--QNYLNPVYSPSFAESQPVLEPSTQAYHFKFWRNM 500

  Fly   565 YLRWVIDQRSSVTVMSQIQELVT-----REKELRTQALKLRKQAMELGQEVSNL 613
            |.::   .||.....|.::.::|     ||.|...||||.:.|  .||...|.|
Zfish   501 YHQY---DRSLHPRQSILKNVLTLKESNRELEGTVQALKTKLQ--NLGVSTSPL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_648271.3	PH-GRAM_MTMR9	1..106	CDD:275398	33/100 (33%)
		Myotub-related	210..512	CDD:461958	118/320 (37%)
mtmr6	NP_956085.1	PH-like	1..102	CDD:473070	35/105 (33%)
		PTP-MTMR6	131..432	CDD:350433	115/378 (30%)