DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5026 and Mtmr10

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_001094316.1	Gene:	Mtmr10 / 309255	RGDID:	1305958	Length:	771	Species:	Rattus norvegicus

Alignment Length:	562	Identity:	135/562 - (24%)
Similarity:	233/562 - (41%)	Gaps:	141/562 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KTPKLDGVLLHDPSNAGASGATVGTLCITGHHLLLSARQETSQ-ELW--LLHKN----------- 58
            |..||:.|||  |.....:.......||.         .:||| :||  |:..|
  Rat    30 KIKKLEPVLL--PGEIVVNEVNFVRKCIA---------TDTSQYDLWGKLICSNFKISFITDDPM 83

  Fly    59 ------------------IDCVEKKPSLS----QNIVVGGIITLK---------CKDLRIISLEI 92
                              :.|:|:..:::    :..|:|....||         |||.||:....
  Rat    84 PLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRF 148

  Fly    93 -KCGKEFF-NVAASLEALSAIQNTELLYPFFYRPMYSILEDGYTMFRPELEFAKLISGVGMGGAS 155
             :.|.|.. .|..::...|...:.:||:.|.|            :.:.....|..::||..||..
  Rat   149 DESGPESAKKVCLAIAHYSQPTDLQLLFAFEY------------VGKKYHNSANKVNGVSSGGGG 201

  Fly   156 SPNVANITICMPSTSTSTLTVGAGIPH----PLQNGYA---IEALACGVGGVGGGALQSPQASCE 213
                              :..|||.|.    ||...|:   .|....|..|
  Rat   202 ------------------VWSGAGSPSSQRTPLFETYSDWDRETKRTGASG-------------- 234

  Fly   214 WRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSYRHENGATLMRSSQPLSI 278
            ||:.::|..:.:........:||.::.|:.:.:.:....|.|.|...:.|.||:.|:|.:  |..
  Rat   235 WRVCSINEGYMISTCLPEYFVVPSSLADQDLKIFSPSFVGRRMPCWCWSHSNGSALVRMA--LIK 297

  Fly   279 QGIKRCRADEAILNLVLGRSRKGFIVDTWGKGKSNTE-TDLHYSQWKKVNRSIGNVSSPASILDS 342
            ..:::.:.|:.|.|.:.               ||:.: :|::.|.   :::::.|:.   .|..:
  Rat   298 DVLQQRKIDQRICNAIT---------------KSHPQRSDVYKSD---LDKTLPNIQ---EIQAA 341

  Fly   343 FARLIEAC-NDLGCST-DKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDST 405
            |.:|.:.| |:....| :||||.||::.||..|...|..|..:...|:.:...|::...:|.|.:
  Rat   342 FVKLKQLCVNEPFEETEEKWLSSLESTRWLEYVRAFLKHSAELVYILESQRLSVVLQEEEGRDLS 406

  Fly   406 LIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFASRHRYSCYTPNQTRNKTSGATFVLFLDC 470
            .:|.||||::::|..||:.|.|:|:::||:.||:||..|..:      ..|::.....|:||||.
  Rat   407 CLVASLVQVMMDPYFRTITGFQSLVQKEWVMAGYPFLDRCNH------LKRSEKESPLFLLFLDT 465

  Fly   471 IYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERER 512
            .:||..|:|.:||||...|.:|.:.:..|.:||||.:|..:|
  Rat   466 TWQLLEQYPAAFEFSETYLAVLCDSTRISLFGTFLFNSPHQR 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398	30/144 (21%)
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	102/403 (25%)
Mtmr10	NP_001094316.1	PH-GRAM_MTMR10	21..193	CDD:270154	36/185 (19%)
		PTPc	222..503	CDD:304379	86/323 (27%)
		3-PAP	574..701	CDD:289355
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1089
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740