DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5026 and Mtmr3

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_006251364.1	Gene:	Mtmr3 / 305482	RGDID:	1310972	Length:	1207	Species:	Rattus norvegicus

Alignment Length:	413	Identity:	131/413 - (31%)
Similarity:	196/413 - (47%)	Gaps:	71/413 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 WRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSYRHE-NGATLMRSSQP-L 276
            |||:|:|..:.:|.:|...||||..|||:::...|.||...|.|.:.|||: |||.:.|..|| :
  Rat   176 WRISNINEKYKLCGSYPQELIVPAWITDKELESVAGFRSWKRIPAVIYRHQSNGAVIARCGQPEV 240

  Fly   277 S------------IQGI-KRCRAD----------------------------EAILNLVLG---- 296
            |            :|.: |.|.:|                            :|.|:...|
  Rat   241 SWWGWRNADDEHLVQSVAKACASDSQSSVGKVSTRNSCRGFPNAGDLSDVEFDASLSNASGTESL 305

  Fly   297 --RSRKGFIVD---------TWGKGKSNTETDLHYSQWKKVNRSIGNVSSPASILDSFARLIEAC 350
              :.:|..|:|         ...|| ...|...:|...:.|...:.|:.   ||..||..|...|
  Rat   306 ALQPQKLLILDARSYAAAVANRAKG-GGCECPEYYPNCEVVFMGMANIH---SIRRSFQSLRLLC 366

  Fly   351 NDLGCSTDKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQII 415
            ..:. ....|||.||::.||..:...|.::.:|...:|::..|||||.:.|.|.|..:.:|.:::
  Rat   367 TQMP-DPGNWLSALESTKWLHHLSVLLKSALLVVHAVDRDQRPVLVHCSDGWDRTPQIVALAKLL 430

  Fly   416 LNPDCRTVRGLQALIEREWIQAGHPFASRHRYSC-YTPNQTRNKTSGATFVLFLDCIYQLYTQFP 479
            |:|..|||.|.|.|:|.||:..||.||.|    | :..|..........|:.:|||::||..|||
  Rat   431 LDPYYRTVEGFQVLVEMEWLDFGHKFADR----CGHGENSDDLNERCPVFLQWLDCVHQLQRQFP 491

  Fly   480 CSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLYEP 544
            |||||:...|:.|.:|::...:|||||::.:||.|.....||.|:||.|...:  :.|.|.||..
  Rat   492 CSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKQTQERTCSVWSLLRAGN--KAFKNLLYSS 554

  Fly   545 NAN-VIWPSVAPISLELWSDLYL 566
            .:. |::|.....:|.|||.:||
  Rat   555 QSEAVLYPVCHVRNLMLWSAVYL 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	110/355 (31%)
Mtmr3	XP_006251364.1	PH-GRAM_MTMR3	23..116	CDD:270149
		PTP-MTMR3	169..485	CDD:350434	92/317 (29%)
		FYVE_MTMR3	1115..1184	CDD:277271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349519
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850